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- W3150188006 abstract "but sharply demarcated from the surrounding connective tissue (Fig 2). The tumors contained a peripheral arrangement of plump, spindle shaped cells resembling myofibroblasts surrounding centrally located vascular components with a staghorn or hemangiopericytoma-like appearance. The lesions were smooth muscle actinepositive and desmin-negative. The patient underwent eight additional excisions of existing and new lesions over the next 17 months, each showing similar microscopic and histochemical patterns. No evidence of recurrence following excision was observed. Reports of multiple myofibromas presenting in adulthood are uncommon. It is feasible that such occurrences are underreported based on the diagnosis of entities that can share similar clinical and/or microscopic characteristics. Diagnoses of consideration include angioma, dermatofibroma, fibromatosis, hemangiopericytoma, keloid, lipoma, leiomyoma, leiomyosarcoma, and neurofibroma. A microscopic resemblance to hemangiopericytomas, which lack the spindle cell fascicles often seen in myofibromas, may create confusion regarding a lesion’s malignant potential. Similarly, hereditary leiomyomatosis cutis, a collection of desminpositive lesions, has been associated with underlying uterine leiomyomata and renal cell carcinoma. Myofibromas are not associated with malignancy, and proper diagnosis is beneficial, because most series have shown few episodes of recurrence following excision." @default.
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- W3150188006 date "2011-01-01" @default.
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- W3150188006 title "Complete basal cell carcinoma remission with imiquimod in a patient with nevoid basal cell carcinoma syndrome and associated basal cell carcinoma of the scalp and invasive ductal breast cancer" @default.
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