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- W3150404932 abstract "瞄准：调查 vacuolating 细胞毒素(休假 A ) 的流行，细胞毒素联系了基因 A (cagA ) 和 pylori (H pylori ) 从古巴的消化不良的病人孤立的 Helicobacter 的血粘附绑定抗原(babA2 ) 遗传型。方法：DNA 从从 130 个消化不良的病人拿的 H pylori 积极的文化被提取。Genotyping 被 PCR 执行，用为休假 A 的特定的教材(s1， s2， m1， m2 ) ， cagA 和 babA2 基因。内视镜的观察和组织学的考试被用来决定耐心的病理。结果：休假 A 等位基因 s1， s2， m1 和 m2 在 96 被检测(73.8%) ， 34 (26.2%) ， 75 (57.7%) 并且 52 孤立(40%) ，分别地当 cagA 基因在 95 被检测时孤立(73.2%) 。107 孤立(82.3%) 是 babA2 积极的。重要关联在 vacAs1m1 和 cagA 之间并且在 vacAs1m1 和 babA2 遗传型之间被观察(P < 0.001 并且 P < 0.05，分别地) 并且在 babA2 遗传型和 cagA 地位之间(P < 0.05 ) ；但是，没有关联在 vacAs1 和 babA2 遗传型之间被观察。八十五(65.4%) 并且 73 (56.2%) 紧张是类型 1 (vacAs1-cagA-positive ) 并且“三元组积极”(vacAs1-cagA-babA2-positive ) ，分别地并且他们的存在显著地与十二指肠的溃疡被联系(P < 0.01 并且 P < 0.001，分别地) 。结论：在在这研究的古巴的紧张的主要毒力因素的分发类似于西方类型的紧张，和更剧毒的 H pylori 的孤立显著地与十二指肠的溃疡被联系，是的溃疡疾病在这个组观察的最糟的病理学习了。" @default.
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- W3150404932 date "2009-01-01" @default.
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- W3150404932 title "Prevalence of vacA, cagA and babA2 genes in Cuban Helicobacter pylori isolates" @default.
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