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• W3150487918 abstract "Abstract Researches proving methods for nano-encapsulation of neonatal porcine islet-like cell clusters (NPCCs) using polymersomes (PSomes) formed using polymers of polyethylene glycol-block-poly lactide. Herein, our studies present efficient nano-encapsulation procedure with minimal damage and loss of NPCCs.We used N-hydroxysuccinimide (NHS) on the N-terminal of PSomes to induce binding of amine groups in the extracellular matrix surrounding NPCCs. F-10 culture medium with bovine serum albumin was used in the nano-encapsulation procedure to minimize damage and loss of NPCCs. Finally, we induced cross-linking between bifunctional PSomes (NHS-/NH 2 -PSomes). F-10 culture medium containing 0.25% BSA with pH of 7.3 minimized the damage and loss of NPCCs after nano-encapsulation as compared with using basic HBSS buffer (pH 8.0). Also, we induced the efficient nano-encapsulation through conjugation of PSomes using bifunctional PSomes (NHS-/NH 2 -PSomes)." @default.
• W3150487918 created "2021-04-13" @default.
• W3150487918 creator A5019886336 @default.
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• W3150487918 date "2021-03-31" @default.
• W3150487918 modified "2023-10-18" @default.
• W3150487918 title "Optimization of Nano-encapsulation on Neonatal Porcine Islet-like Cell Clusters Using Polymersomes" @default.
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• W3150487918 doi "https://doi.org/10.1186/s11671-021-03512-3" @default.
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