FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3150524678> ?p ?o ?g. }

• W3150524678 abstract "In order to investigate the effects of lead exposure on risk of cardiovascular disease during occupational exposure to this metal, plasma cholesterol and its fractions as high-density liporotein (HDL), low-density liporotein (LDL) and triglyceride were determined in various artisans in Abeokuta, Nigeria who have been shown to be occupationally exposed to lead and these were related to blood lead levels. Increased risk of cardiovascular disease was observed in the artisans. Total cholesterol in the artisans was between 1.5 and 2.0 times higher in the artisans than that present in controls while LDL cholesterol was between 1.6 and 2.4 times higher in the artisans when compared with control subjects [p 0.05]. A significant positive correlation was observed between blood lead and total cholesterol on one hand [r = 0.372; p = 3.0 × 10-5] and blood lead and LDL cholesterol on the other hand [r = 0.283; p = 0.001]. LDL/HDL cholesterol ratio was also higher in the artisans when compared with control. Blood pressure (systolic and diastolic) and other anthropometric parameters were not significantly different between the artisans and the control subjects [p > 0.05]. Results suggest that lead exposure increases cholesterol synthesis and transport to peripheral tissues whereas reverse cholesterol transport to the liver is not affected. Introduction Studies in both humans and animals indicate that lipid metabolism is altered in chronic lead exposure [1-6]. The pathophysiological mechanisms involved in this leadinduced alterations are not completely understood. Lead has been shown to accelerate lipid oxidation in the presence of hemoglobin or Fe2+ [7,8]. Lead was also shown to enhance Fe2+-initiated lipid oxidation in liposomes, erythrocytes, microsomal fractions and rat brain homogenates [1,7,9]. Altered fatty acid composition of erythrocyte membranes has also been demonstrated in chronic lead exposure [5,10,11]. It has also been demonstrated that lead exposure affects levels of galactolipid metabolic enzymes in the developing rat brain resulting in myelin defects [3]. All these observations are largely more suggestive than conclusive about lead-induced alterations in lipid metabolism. Lead poisoning is presently becoming the most common disease of environmental origin and is increasing very Published: 28 September 2005 Lipids in Health and Disease 2005, 4:19 doi:10.1186/1476-511X-4-19 Received: 31 August 2005 Accepted: 28 September 2005 This article is available from: http://www.lipidworld.com/content/4/1/19 © 2005 Ademuyiwa et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited." @default.
• W3150524678 created "2021-04-13" @default.
• W3150524678 creator A5040659573 @default.
• W3150524678 creator A5041273574 @default.
• W3150524678 creator A5047122906 @default.
• W3150524678 creator A5053318769 @default.
• W3150524678 date "2015-01-01" @default.
• W3150524678 modified "2023-10-08" @default.
• W3150524678 title "Lipids in Health and Disease" @default.
• W3150524678 cites W130256847 @default.
• W3150524678 cites W1774786172 @default.
• W3150524678 cites W1831764796 @default.
• W3150524678 cites W1861709718 @default.
• W3150524678 cites W1964354937 @default.
• W3150524678 cites W1974182758 @default.
• W3150524678 cites W2000954101 @default.
• W3150524678 cites W2010463148 @default.
• W3150524678 cites W2027846645 @default.
• W3150524678 cites W2029210533 @default.
• W3150524678 cites W2032043946 @default.
• W3150524678 cites W2037444529 @default.
• W3150524678 cites W2038769339 @default.
• W3150524678 cites W2038998803 @default.
• W3150524678 cites W2040675110 @default.
• W3150524678 cites W2043840023 @default.
• W3150524678 cites W2052368044 @default.
• W3150524678 cites W2052776501 @default.
• W3150524678 cites W2053259746 @default.
• W3150524678 cites W2061077214 @default.
• W3150524678 cites W2061986532 @default.
• W3150524678 cites W2066688265 @default.
• W3150524678 cites W2087169447 @default.
• W3150524678 cites W2092516111 @default.
• W3150524678 cites W2095570321 @default.
• W3150524678 cites W2116560673 @default.
• W3150524678 cites W2117973794 @default.
• W3150524678 cites W2129788418 @default.
• W3150524678 cites W2136524105 @default.
• W3150524678 cites W2141599510 @default.
• W3150524678 cites W2141997059 @default.
• W3150524678 cites W2146334297 @default.
• W3150524678 cites W2146478570 @default.
• W3150524678 cites W2153609395 @default.
• W3150524678 cites W2153804011 @default.
• W3150524678 cites W2155063465 @default.
• W3150524678 cites W2165131979 @default.
• W3150524678 cites W2189623052 @default.
• W3150524678 cites W2285846084 @default.
• W3150524678 cites W2291625427 @default.
• W3150524678 cites W2318364818 @default.
• W3150524678 cites W2339616051 @default.
• W3150524678 cites W2410759241 @default.
• W3150524678 cites W2499930093 @default.
• W3150524678 cites W2765058379 @default.
• W3150524678 cites W41922719 @default.
• W3150524678 cites W78205317 @default.
• W3150524678 cites W2004402590 @default.
• W3150524678 cites W2032525547 @default.
• W3150524678 cites W2077709248 @default.
• W3150524678 hasPublicationYear "2015" @default.
• W3150524678 type Work @default.
• W3150524678 sameAs 3150524678 @default.
• W3150524678 citedByCount "0" @default.
• W3150524678 crossrefType "journal-article" @default.
• W3150524678 hasAuthorship W3150524678A5040659573 @default.
• W3150524678 hasAuthorship W3150524678A5041273574 @default.
• W3150524678 hasAuthorship W3150524678A5047122906 @default.
• W3150524678 hasAuthorship W3150524678A5053318769 @default.
• W3150524678 hasConcept C126322002 @default.
• W3150524678 hasConcept C134018914 @default.
• W3150524678 hasConcept C2776431099 @default.
• W3150524678 hasConcept C2778163477 @default.
• W3150524678 hasConcept C2778913445 @default.
• W3150524678 hasConcept C2779904517 @default.
• W3150524678 hasConcept C2780541478 @default.
• W3150524678 hasConcept C3020026551 @default.
• W3150524678 hasConcept C71924100 @default.
• W3150524678 hasConcept C84393581 @default.
• W3150524678 hasConceptScore W3150524678C126322002 @default.
• W3150524678 hasConceptScore W3150524678C134018914 @default.
• W3150524678 hasConceptScore W3150524678C2776431099 @default.
• W3150524678 hasConceptScore W3150524678C2778163477 @default.
• W3150524678 hasConceptScore W3150524678C2778913445 @default.
• W3150524678 hasConceptScore W3150524678C2779904517 @default.
• W3150524678 hasConceptScore W3150524678C2780541478 @default.
• W3150524678 hasConceptScore W3150524678C3020026551 @default.
• W3150524678 hasConceptScore W3150524678C71924100 @default.
• W3150524678 hasConceptScore W3150524678C84393581 @default.
• W3150524678 hasLocation W31505246781 @default.
• W3150524678 hasOpenAccess W3150524678 @default.
• W3150524678 hasPrimaryLocation W31505246781 @default.
• W3150524678 hasRelatedWork W196783855 @default.
• W3150524678 hasRelatedWork W1969859921 @default.
• W3150524678 hasRelatedWork W2018245168 @default.
• W3150524678 hasRelatedWork W2019988977 @default.
• W3150524678 hasRelatedWork W2112264279 @default.
• W3150524678 hasRelatedWork W2113964492 @default.
• W3150524678 hasRelatedWork W2119957995 @default.
• W3150524678 hasRelatedWork W2185729181 @default.
• W3150524678 hasRelatedWork W2186786719 @default.

• next