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- W3150554795 abstract "Gastric ulcers are one of the most common stomach diseases that often accompanied by inflammation, congestion, edema, scar tissue formation, and pyloric obstruction. Fiberoptic endoscopy and X-ray analysis of the upper GI tract have become the diagnostic procedure of choice for patients. However, conventional diagnosis technology is either invasive or radioactive. Herein, a novel CD-MOF NIR-II fluorophore (GPs-CH1055) was developed. The relative fluorophore intensity was largely consistent at various media and pH buffers, and it can swell into gel particles in solvents and be completely expelled from the gastrointestinal tract without being assimilated. GPs-CH1055 has been further evaluated in vivo, and exhibited strong retention effect on the gastric ulcer sites, bright NIR-II signals with high spatial and temporal resolution. Therefore, GPs-CH1055 shows great promise for realizing real-time gastric ulcer imaging and diagnosis." @default.
- W3150554795 created "2021-04-13" @default.
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- W3150554795 date "2021-10-01" @default.
- W3150554795 modified "2023-10-01" @default.
- W3150554795 title "Novel CD-MOF NIR-II fluorophores for gastric ulcer imaging" @default.
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- W3150554795 doi "https://doi.org/10.1016/j.cclet.2021.03.075" @default.
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