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- W3150632110 abstract "我们利用了唯一的耕灼度分析基因，蛋白质，和房间表面的表示模式相关基因 inerythroid 和 myeloid 区别的抗原，和生物学过程并且响应 cytokine 改变造血的干细胞(HSC ) 切换。基因特定的碎片(266 ) 从五张人口鉴别刺激 ofcytokine 的 HSC 被分成三个组：(1 ) 在一张单个房间人口明确地表示了；(2 ) 在二张房间人口表示了，并且(3 ) 在三表示了或更多的人口。145 定义 cDNAs，(2%) 三是新奇基因。显示出的蛋白质二维的胶化电气泳动和流动 cytometry 分析重叠了并且在人口学习了的房间区分了蛋白质表示侧面。生物学过程印射在 erythroidand myeloid 系表示的 mRNAs 显示 mRNAs 由出席的两个系分享了“核心过程，“而明确地独自在任何一个系表示的基因与特定的过程或细胞的成熟有关。从这研究的数据支持承诺了 HSC (E14 或 G14 ) 的假设当 erythropoietin (EPO ) 被分别地在 myeloid 有教养的环境与 EPO 在 erythroid 有教养的条件 orG-CSF 下面刺激因素(G-CSF ) 的 granulocyte 殖民地代替时，房间能仍然被重定向发展成 myeloid 或 erythroid 房间。我们的结果建议基因或蛋白质在 erythroid 共同表示， myeloid 系可能为系维护是必要的并且在造血作用切换。" @default.
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- W3150632110 date "2006-01-01" @default.
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- W3150632110 title "Identification of key genes responsible for cytokine-induced erythroid and myeloid differentiation and switching of hematopoietic stem cells by RAGE" @default.
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