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- W3150942004 abstract "Abstract Detection of idiopathic interstitial pneumonias (IIPs) on chest X-ray is difficult for non-specialist physicians, especially in patients with mild IIPs. The current study aimed to evaluate the usefulness of a simple method for detecting IIPs by measuring vertical lung length (VLL) in chest X-rays to quantify decreased lung volume. A total of 280 consecutive patients with IIPs were randomly allocated to exploratory and validation cohorts, and 140 controls were selected for each cohort by propensity score-matching. Upper ( u VLL; from apex to tracheal carina), lower ( l VLL; from carina to costophrenic angle), and total VLL ( t VLL; from apex to costophrenic angle), and the l / u VLL ratio were measured on chest X-rays. Patients in the exploratory cohort had significantly decreased u VLL, l VLL, t VLL, and l / u VLL ratio compared with controls (all p < 0.001). Receiver operating characteristic curve analyses demonstrated that l VLL (area under the curve [AUC] 0.86, sensitivity 0.65, specificity 0.92), t VLL (AUC 0.83, sensitivity 0.75, specificity 0.80), and l / u VLL ratio (AUC 0.80, sensitivity 0.72, specificity 0.79) had high diagnostic accuracies for IIPs. These results were reproduced in the validation cohort. IIP patients thus have decreased VLLs, and measurements of VLL may thus aid the accurate detection of IIPs." @default.
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- W3150942004 date "2021-04-07" @default.
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- W3150942004 title "Simple method for detecting idiopathic interstitial pneumonias by measuring vertical lung length on chest X-ray" @default.
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- W3150942004 doi "https://doi.org/10.1038/s41598-021-87452-z" @default.
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