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- W3150996474 abstract "瞄准：决定杂种狗枯茗是否阻止血小板的粘附到大脑微脉管的 endothelial (BMEC ) 有教养的在试管内。方法：[3H ] Ad-enine-labeled 血小板与 BMEC 被孵化在对 BMEC 的血小板的粘附调查杂种狗枯茗的角色。遵守 BMEC 单层的血小板的数字被液体焕发光谱学决定。血小板 P-selectin，糖蛋白 Hb (GPIIb ) ，和房间上的糖蛋白 IIIa (GPIIIa ) 的导致凝血酵素的表示出现，被流动血细胞计数测量。BMEC 的 P-selectin mRNA 层次被 RT-PCR 决定。TNF- α - 导致了 P-selectin 的表情， BMEC 的表面上的 E-selectin 被西方的弄污决定。结果：在 thrombin-acti-vated 血小板和正常之间的粘附 BMEC，和 TNF- α - 的激活 BMEC 和正常血小板显著地被增加，并且这增加能被杂种狗枯茗(30-240 μ m ol/L ) 以一种集中家属方式禁止。与 TNF- α刺激的凝血酵素和 BMEC 激活的血小板示威了一起来 P-selectin 和 E-selectin 的调整表情，和这增加有为 30 min 的杂种狗枯茗的 pretreated，能被制止剂量依赖地。姜黄色素也以一种集中依赖者方式禁止了激活凝血酵素的血小板的 GPIIb/GPIIIa 表示的增加。结论：姜黄色素能禁止血小板到 BMEC。这效果可能与血小板和 BMEC 上的 P-selectin， E-selectin，和 GPIIb/GPIIIa 的减少的表情有关。" @default.
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- W3150996474 date "2008-01-01" @default.
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