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- W3150998046 abstract "Cyclic stretch increases Na ? /K ? -ATPase activity and abundance in several tissues, including skeletal muscle cells. The present study was undertaken to inves- tigate whether Na ? /K ? -ATPase undergoes acute changes in its catalytic activity in response to cyclic stretch. Na ? / K ? -ATPase activity increased after continuously stretched for 6 h, and reached the maximum at 24 h. The inhibition of gene transcription (actinomycin D) had no effect on stretch-induced Na ? /K ? -ATPase activity. Cyclic stretch also increases the plasma membrane content of a1- and a2- subunit of Na ? /K ? -ATPase. Brefeldin A could completely abolished the stretch-induced recruitment of a-subunits to the plasma membrane and Na ? /K ? -ATPase activity. In" @default.
- W3150998046 created "2021-04-13" @default.
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- W3150998046 date "2012-01-01" @default.
- W3150998046 modified "2023-09-27" @default.
- W3150998046 title "Cyclic stretch stimulates recruitment of active Na + /K + -ATPase subunits to the plasma membrane of skeletal muscle cells" @default.
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