FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3151077222> ?p ?o ?g. }

• W3151077222 endingPage "175" @default.
• W3151077222 startingPage "165" @default.
• W3151077222 abstract "Prokinetics can be used for treating patients with gastroesophageal reflux disease (GERD), who exhibit suboptimal response to proton pump inhibitor (PPI) treatment. We conducted a systematic review to assess the potential benefits of combination treatment with PPI plus prokinetics in GERD.We searched PubMed, the Cochrane Library, and EMBASE for publications regarding randomized controlled trials comparing combination treatment of PPI plus prokinetics to PPI monotherapy with respect to global symptom improvement in GERD (until February 2020). The primary outcome was an absence or global symptom improvement in GERD. Adverse events and quality of life (QoL) scores were evaluated as secondary outcomes using a random effects model. Quality of evidence was rated using Grading of Recommendations, Assessment, Development, and Evaluation (GRADE).This meta-analysis included 16 studies involving 1446 participants (719 in the PPI plus prokinetics group and 727 in the PPI monotherapy group). The PPI plus prokinetics treatment resulted in a significant reduction in global symptoms of GERD regardless of the prokinetic type, refractoriness, and ethnicity. Additionally, treatment with PPI plus prokinetics for at least 4 weeks was found to be more beneficial than PPI monotherapy with respect to global symptom improvement. However, the QoL scores were not improved with PPI plus prokinetics treatment. Adverse events observed in response to PPI plus prokinetics treatment did not differ from those observed with PPI monotherapy.Combination of prokinetics with PPI treatment is more effective than PPI alone in GERD patients. Further high-quality trials with large sample sizes are needed to verify the effects based on prokinetic type." @default.
• W3151077222 created "2021-04-13" @default.
• W3151077222 creator A5002019824 @default.
• W3151077222 creator A5005297881 @default.
• W3151077222 creator A5038843451 @default.
• W3151077222 creator A5063700949 @default.
• W3151077222 creator A5069484753 @default.
• W3151077222 creator A5085725295 @default.
• W3151077222 date "2021-04-30" @default.
• W3151077222 modified "2023-10-16" @default.
• W3151077222 title "A Systematic Review and Meta-analysis of Randomized Control Trials: Combination Treatment With Proton Pump Inhibitor Plus Prokinetic for Gastroesophageal Reflux Disease" @default.
• W3151077222 cites W1534385499 @default.
• W3151077222 cites W1935581134 @default.
• W3151077222 cites W2001782466 @default.
• W3151077222 cites W2004055492 @default.
• W3151077222 cites W2028221809 @default.
• W3151077222 cites W2030758986 @default.
• W3151077222 cites W2041238628 @default.
• W3151077222 cites W2047172704 @default.
• W3151077222 cites W2047953060 @default.
• W3151077222 cites W2071521423 @default.
• W3151077222 cites W2084253090 @default.
• W3151077222 cites W2094443594 @default.
• W3151077222 cites W2100952960 @default.
• W3151077222 cites W2106330907 @default.
• W3151077222 cites W2125435699 @default.
• W3151077222 cites W2138748021 @default.
• W3151077222 cites W2154293008 @default.
• W3151077222 cites W2158690779 @default.
• W3151077222 cites W2314739030 @default.
• W3151077222 cites W2345655271 @default.
• W3151077222 cites W2417894215 @default.
• W3151077222 cites W2463786643 @default.
• W3151077222 cites W2576440140 @default.
• W3151077222 cites W2588346002 @default.
• W3151077222 cites W2588681363 @default.
• W3151077222 cites W2616942973 @default.
• W3151077222 cites W2744685332 @default.
• W3151077222 cites W2900539152 @default.
• W3151077222 cites W2907561542 @default.
• W3151077222 cites W2963391544 @default.
• W3151077222 cites W3021576283 @default.
• W3151077222 cites W4231263040 @default.
• W3151077222 cites W4232718736 @default.
• W3151077222 cites W62416697 @default.
• W3151077222 doi "https://doi.org/10.5056/jnm20161" @default.
• W3151077222 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8026378" @default.
• W3151077222 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33795539" @default.
• W3151077222 hasPublicationYear "2021" @default.
• W3151077222 type Work @default.
• W3151077222 sameAs 3151077222 @default.
• W3151077222 citedByCount "14" @default.
• W3151077222 countsByYear W31510772222021 @default.
• W3151077222 countsByYear W31510772222022 @default.
• W3151077222 countsByYear W31510772222023 @default.
• W3151077222 crossrefType "journal-article" @default.
• W3151077222 hasAuthorship W3151077222A5002019824 @default.
• W3151077222 hasAuthorship W3151077222A5005297881 @default.
• W3151077222 hasAuthorship W3151077222A5038843451 @default.
• W3151077222 hasAuthorship W3151077222A5063700949 @default.
• W3151077222 hasAuthorship W3151077222A5069484753 @default.
• W3151077222 hasAuthorship W3151077222A5085725295 @default.
• W3151077222 hasBestOaLocation W31510772221 @default.
• W3151077222 hasConcept C126322002 @default.
• W3151077222 hasConcept C168563851 @default.
• W3151077222 hasConcept C197934379 @default.
• W3151077222 hasConcept C2776478404 @default.
• W3151077222 hasConcept C2777014526 @default.
• W3151077222 hasConcept C2779134260 @default.
• W3151077222 hasConcept C2781025758 @default.
• W3151077222 hasConcept C43270747 @default.
• W3151077222 hasConcept C71924100 @default.
• W3151077222 hasConcept C90924648 @default.
• W3151077222 hasConcept C95190672 @default.
• W3151077222 hasConceptScore W3151077222C126322002 @default.
• W3151077222 hasConceptScore W3151077222C168563851 @default.
• W3151077222 hasConceptScore W3151077222C197934379 @default.
• W3151077222 hasConceptScore W3151077222C2776478404 @default.
• W3151077222 hasConceptScore W3151077222C2777014526 @default.
• W3151077222 hasConceptScore W3151077222C2779134260 @default.
• W3151077222 hasConceptScore W3151077222C2781025758 @default.
• W3151077222 hasConceptScore W3151077222C43270747 @default.
• W3151077222 hasConceptScore W3151077222C71924100 @default.
• W3151077222 hasConceptScore W3151077222C90924648 @default.
• W3151077222 hasConceptScore W3151077222C95190672 @default.
• W3151077222 hasFunder F4320322120 @default.
• W3151077222 hasIssue "2" @default.
• W3151077222 hasLocation W31510772221 @default.
• W3151077222 hasLocation W31510772222 @default.
• W3151077222 hasLocation W31510772223 @default.
• W3151077222 hasLocation W31510772224 @default.
• W3151077222 hasOpenAccess W3151077222 @default.
• W3151077222 hasPrimaryLocation W31510772221 @default.
• W3151077222 hasRelatedWork W1597918229 @default.
• W3151077222 hasRelatedWork W1972259282 @default.
• W3151077222 hasRelatedWork W1977139604 @default.
• W3151077222 hasRelatedWork W1995901896 @default.
• W3151077222 hasRelatedWork W2052569066 @default.

• next