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- W3151512855 abstract "Objective To explore the possibility of prefab ricate a vascul arized artificial bone-muscular flap, a compound of xenogenic inorganic bone an d auto-marrow, with capability of osteogenesis. Methods Twe lve 6-month New Zea land rabbits were divided into two groups, compound of xenogenic inorganic bone and auto-marrow implanted into the muscle near to radia and ulna of left forefo o t as experimental group. Simple xenogenic inorganic bone implanted into the same site of right side as control group. After 2, 8, 12 weeks, x-ray examination, g ross evaluation and histological observation were carried out. Results X-ray film showed that the implant had a cancellus-like density, and no variance with time. Since 2 weeks after implantation, gross observation showed a complete fusi on formed between the implant and the host muscular tissue, with obvious blood v essels on the surface of the muscular flap in which the compound was encapsulate d. No necrosis was observed in the following 30 minutes after the compound was d issected from its surrounding tissues. The histological investigation showed a c ontact connection between implant and its surroundings. In the experimental grou p, no new bone formed but in-growth of blood vessels was observed at the end of the 2nd week, and a little new bone formed along the edge of xenogenic inorganic bone at the end of the 8th week, while at the end of 12th week, more new bone f ormed in the compound with osteocytes in bone lacuna, plenty blood vessels in bo ne matrix, and lots of osteoblasts surrounded by un-differentiated mesenchymal c ells at the fringe of the new bone. While in the control group, there were only loose connective tissue with blood vessels grew into xenogenic inorganic bone wi th no new bone formation until 12 weeks. Conclusion The com pound of xenogenic inorganic bone and auto-marrow can promote the formation of vascularized myo- bone flap with new bone formation." @default.
- W3151512855 created "2021-04-13" @default.
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- W3151512855 date "2001-01-01" @default.
- W3151512855 modified "2023-09-25" @default.
- W3151512855 title "EXPERIMENTAL STUDY ON COMPOUND OF XENOGENIC INORGANIC BONE AND AUTO- MARROW ENCAPSULED BY PEDICLED MUSCULAR FLAP" @default.
- W3151512855 hasPublicationYear "2001" @default.
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