FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3152138974> ?p ?o ?g. }

• W3152138974 endingPage "193" @default.
• W3152138974 startingPage "186" @default.
• W3152138974 abstract "Rett syndrome (RTT) is a severe genetic neurodevelopmental disorder. Emotional, Behavioural and Autonomic Dysregulation (EBAD), is frequent in RTT and is associated with multiple impairments. There are major challenges in the clinical assessment of emotions, behaviours, and autonomic function in RTT patients that limit the management of symptoms. Web-based technology (HealthTracker™) to measure the phenotype, and non-invasive, wearable sensor technology to evaluate autonomic function through Electrodermal Activity (EDA) and Heart Rate Variability (HRV) in 10 RTT patients was used, and treatment response of EBAD symptoms was monitored after different pharmacological treatments. and discussion: 4 patients received buspirone, 2 sertraline, 1 gabapentin and 3 were not started on medications. Buspirone normalized the EDA in 3 patients with associated improvement in EBAD, whilst another patient only improved marginally. Both patients treated with sertraline (including one with normal EDA) significantly improved symptomatically. The patients on unchanged regimens showed no change in symptoms and autonomic function. Within 24 h of our assessment, one patient required intensive inpatient care due to septicaemia – this patient had been on gabapentin and showed a sharp and sustained EDA increase without obvious worsening of emotional and behavioural symptoms. Unlike the EDA, the analyses of HRV metrics did not reveal patterns that were associated with clinical outcomes. Our findings suggest a reasonable association of EDA normalization and symptomatic improvement in RTT subjects with EBAD treated with buspirone and point out its potential application as a measure of dysautonomia in RTT. Very high and sustained EDA levels may be a biomarker for concurrent serious physical illness in RTT." @default.
• W3152138974 created "2021-04-13" @default.
• W3152138974 creator A5035100919 @default.
• W3152138974 creator A5058598560 @default.
• W3152138974 creator A5063028888 @default.
• W3152138974 creator A5077619957 @default.
• W3152138974 date "2021-06-01" @default.
• W3152138974 modified "2023-10-17" @default.
• W3152138974 title "Emotional Behavioural and Autonomic Dysregulation (EBAD) in Rett Syndrome – EDA and HRV monitoring using wearable sensor technology" @default.
• W3152138974 cites W1768551998 @default.
• W3152138974 cites W1972200139 @default.
• W3152138974 cites W1989341770 @default.
• W3152138974 cites W2020386158 @default.
• W3152138974 cites W2050714001 @default.
• W3152138974 cites W2057343637 @default.
• W3152138974 cites W2063840478 @default.
• W3152138974 cites W2063954016 @default.
• W3152138974 cites W2066197188 @default.
• W3152138974 cites W2066619092 @default.
• W3152138974 cites W2075213922 @default.
• W3152138974 cites W2082171245 @default.
• W3152138974 cites W2099517884 @default.
• W3152138974 cites W2120339204 @default.
• W3152138974 cites W2130614276 @default.
• W3152138974 cites W2154057943 @default.
• W3152138974 cites W2172659002 @default.
• W3152138974 cites W2191720120 @default.
• W3152138974 cites W2526053553 @default.
• W3152138974 cites W2559603698 @default.
• W3152138974 cites W2574630332 @default.
• W3152138974 cites W2681805472 @default.
• W3152138974 cites W2759190050 @default.
• W3152138974 cites W2761724488 @default.
• W3152138974 cites W2886334039 @default.
• W3152138974 cites W2892086776 @default.
• W3152138974 cites W2900673884 @default.
• W3152138974 cites W2912732526 @default.
• W3152138974 cites W2916057939 @default.
• W3152138974 cites W2945710102 @default.
• W3152138974 doi "https://doi.org/10.1016/j.jpsychires.2021.03.052" @default.
• W3152138974 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33862302" @default.
• W3152138974 hasPublicationYear "2021" @default.
• W3152138974 type Work @default.
• W3152138974 sameAs 3152138974 @default.
• W3152138974 citedByCount "10" @default.
• W3152138974 countsByYear W31521389742021 @default.
• W3152138974 countsByYear W31521389742022 @default.
• W3152138974 countsByYear W31521389742023 @default.
• W3152138974 crossrefType "journal-article" @default.
• W3152138974 hasAuthorship W3152138974A5035100919 @default.
• W3152138974 hasAuthorship W3152138974A5058598560 @default.
• W3152138974 hasAuthorship W3152138974A5063028888 @default.
• W3152138974 hasAuthorship W3152138974A5077619957 @default.
• W3152138974 hasBestOaLocation W31521389741 @default.
• W3152138974 hasConcept C118552586 @default.
• W3152138974 hasConcept C126322002 @default.
• W3152138974 hasConcept C142724271 @default.
• W3152138974 hasConcept C15744967 @default.
• W3152138974 hasConcept C170493617 @default.
• W3152138974 hasConcept C204787440 @default.
• W3152138974 hasConcept C2775864247 @default.
• W3152138974 hasConcept C2776608144 @default.
• W3152138974 hasConcept C2777287423 @default.
• W3152138974 hasConcept C2777669559 @default.
• W3152138974 hasConcept C2777953023 @default.
• W3152138974 hasConcept C2779134260 @default.
• W3152138974 hasConcept C2779177272 @default.
• W3152138974 hasConcept C2779543035 @default.
• W3152138974 hasConcept C558461103 @default.
• W3152138974 hasConcept C71635504 @default.
• W3152138974 hasConcept C71924100 @default.
• W3152138974 hasConcept C84393581 @default.
• W3152138974 hasConceptScore W3152138974C118552586 @default.
• W3152138974 hasConceptScore W3152138974C126322002 @default.
• W3152138974 hasConceptScore W3152138974C142724271 @default.
• W3152138974 hasConceptScore W3152138974C15744967 @default.
• W3152138974 hasConceptScore W3152138974C170493617 @default.
• W3152138974 hasConceptScore W3152138974C204787440 @default.
• W3152138974 hasConceptScore W3152138974C2775864247 @default.
• W3152138974 hasConceptScore W3152138974C2776608144 @default.
• W3152138974 hasConceptScore W3152138974C2777287423 @default.
• W3152138974 hasConceptScore W3152138974C2777669559 @default.
• W3152138974 hasConceptScore W3152138974C2777953023 @default.
• W3152138974 hasConceptScore W3152138974C2779134260 @default.
• W3152138974 hasConceptScore W3152138974C2779177272 @default.
• W3152138974 hasConceptScore W3152138974C2779543035 @default.
• W3152138974 hasConceptScore W3152138974C558461103 @default.
• W3152138974 hasConceptScore W3152138974C71635504 @default.
• W3152138974 hasConceptScore W3152138974C71924100 @default.
• W3152138974 hasConceptScore W3152138974C84393581 @default.
• W3152138974 hasLocation W31521389741 @default.
• W3152138974 hasOpenAccess W3152138974 @default.
• W3152138974 hasPrimaryLocation W31521389741 @default.
• W3152138974 hasRelatedWork W1992228899 @default.
• W3152138974 hasRelatedWork W2748952813 @default.
• W3152138974 hasRelatedWork W2899084033 @default.
• W3152138974 hasRelatedWork W2971999596 @default.
• W3152138974 hasRelatedWork W3039380028 @default.

• next