FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3152326958> ?p ?o ?g. }

• W3152326958 abstract "The family of Tribbles proteins play many critical nonenzymatic roles and regulate a wide range of key signaling pathways. Tribbles homolog 2 (Trib2) is a pseudo serine/threonine kinase that functions as a scaffold or adaptor in various physiological and pathological processes. Trib2 can interact with E3 ubiquitin ligases and control protein stability of downstream effectors. This protein is induced by mitogens and enhances the propagation of several cancer cells, including myeloid leukemia, liver, lung, skin, bone, brain, and pancreatic. Thus, Trib2 can be a predictive and valuable biomarker for the diagnosis and treatment of cancer. Recent studies have illustrated that Trib2 plays a major role in cell fate determination of stem cells. Stem cells have the capacity to self-renew and differentiate into specific cell types. Stem cells are important sources for cell-based regenerative medicine and drug screening. Trib2 has been found to increase the self-renewal ability of embryonic stem cells, the reprogramming efficiency of somatic cells, and chondrogenesis. In this review, we will focus on the recent advances of Trib2 function in tumorigenesis and stem cell fate decisions. Video abstract." @default.
• W3152326958 created "2021-04-13" @default.
• W3152326958 creator A5021117572 @default.
• W3152326958 creator A5044265593 @default.
• W3152326958 creator A5062326562 @default.
• W3152326958 creator A5066533204 @default.
• W3152326958 creator A5069899769 @default.
• W3152326958 creator A5077676845 @default.
• W3152326958 creator A5089705035 @default.
• W3152326958 date "2021-04-01" @default.
• W3152326958 modified "2023-09-27" @default.
• W3152326958 title "Tribbles homolog 2 (Trib2), a pseudo serine/threonine kinase in tumorigenesis and stem cell fate decisions" @default.
• W3152326958 cites W1481314844 @default.
• W3152326958 cites W1856178612 @default.
• W3152326958 cites W1964526894 @default.
• W3152326958 cites W1966822894 @default.
• W3152326958 cites W1974351849 @default.
• W3152326958 cites W1987480626 @default.
• W3152326958 cites W1988805027 @default.
• W3152326958 cites W1990142715 @default.
• W3152326958 cites W1991043567 @default.
• W3152326958 cites W2002631420 @default.
• W3152326958 cites W2042060958 @default.
• W3152326958 cites W2046997551 @default.
• W3152326958 cites W2054666013 @default.
• W3152326958 cites W2059777480 @default.
• W3152326958 cites W2062765055 @default.
• W3152326958 cites W2089936989 @default.
• W3152326958 cites W2092664001 @default.
• W3152326958 cites W2094920355 @default.
• W3152326958 cites W2133904591 @default.
• W3152326958 cites W2137979471 @default.
• W3152326958 cites W2148149902 @default.
• W3152326958 cites W2154525215 @default.
• W3152326958 cites W2157845607 @default.
• W3152326958 cites W2160761064 @default.
• W3152326958 cites W2173060614 @default.
• W3152326958 cites W2173150367 @default.
• W3152326958 cites W2279736087 @default.
• W3152326958 cites W2298343038 @default.
• W3152326958 cites W2300552754 @default.
• W3152326958 cites W2346269401 @default.
• W3152326958 cites W2405142225 @default.
• W3152326958 cites W2507893670 @default.
• W3152326958 cites W2510418728 @default.
• W3152326958 cites W2559634823 @default.
• W3152326958 cites W2566429177 @default.
• W3152326958 cites W2583773047 @default.
• W3152326958 cites W2588779593 @default.
• W3152326958 cites W2594883857 @default.
• W3152326958 cites W2769025282 @default.
• W3152326958 cites W2770878806 @default.
• W3152326958 cites W2793118977 @default.
• W3152326958 cites W2802615563 @default.
• W3152326958 cites W2809252818 @default.
• W3152326958 cites W2887294251 @default.
• W3152326958 cites W2892857541 @default.
• W3152326958 cites W2896532260 @default.
• W3152326958 cites W2901194947 @default.
• W3152326958 cites W2904862932 @default.
• W3152326958 cites W2910514691 @default.
• W3152326958 cites W2921086847 @default.
• W3152326958 cites W2921157237 @default.
• W3152326958 cites W2948692231 @default.
• W3152326958 cites W2963298763 @default.
• W3152326958 cites W2966139660 @default.
• W3152326958 cites W2980518695 @default.
• W3152326958 cites W2982542168 @default.
• W3152326958 cites W2990213668 @default.
• W3152326958 cites W2991495895 @default.
• W3152326958 cites W2996314535 @default.
• W3152326958 cites W2997434172 @default.
• W3152326958 cites W2998373386 @default.
• W3152326958 cites W2999431537 @default.
• W3152326958 cites W3012423103 @default.
• W3152326958 cites W3012508263 @default.
• W3152326958 cites W3033755538 @default.
• W3152326958 cites W3040655794 @default.
• W3152326958 cites W3080464487 @default.
• W3152326958 cites W3087131934 @default.
• W3152326958 cites W3087140673 @default.
• W3152326958 cites W3110746819 @default.
• W3152326958 cites W3118425911 @default.
• W3152326958 cites W4289604926 @default.
• W3152326958 cites W4376453125 @default.
• W3152326958 doi "https://doi.org/10.1186/s12964-021-00725-y" @default.
• W3152326958 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8015142" @default.
• W3152326958 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33794905" @default.
• W3152326958 hasPublicationYear "2021" @default.
• W3152326958 type Work @default.
• W3152326958 sameAs 3152326958 @default.
• W3152326958 citedByCount "8" @default.
• W3152326958 countsByYear W31523269582021 @default.
• W3152326958 countsByYear W31523269582022 @default.
• W3152326958 countsByYear W31523269582023 @default.
• W3152326958 crossrefType "journal-article" @default.
• W3152326958 hasAuthorship W3152326958A5021117572 @default.
• W3152326958 hasAuthorship W3152326958A5044265593 @default.
• W3152326958 hasAuthorship W3152326958A5062326562 @default.
• W3152326958 hasAuthorship W3152326958A5066533204 @default.

• next