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• W3152364952 abstract "Three new tyramine-type alkamides (1-3), three new natural products (4-6), five new N-acylated/formylated aporphine alkamides with different ratios of rotational isomers (7-11), and 20 known alkamides (12-31) were isolated from an EtOH extract of the stems and leaves of Piper puberulum. The absolute configurations of compounds 7, 8, and 10 were determined by single-crystal X-ray diffraction analysis. In the biological activity assay, compounds 3, 5, and 10-23 displayed inhibitory effects against lipopolysaccharide-induced NO release in BV-2 microglial cells, exhibiting IC50 values of 0.93-45 μM." @default.
• W3152364952 created "2021-04-13" @default.
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• W3152364952 date "2021-04-06" @default.
• W3152364952 modified "2023-10-16" @default.
• W3152364952 title "New Tyramine- and Aporphine-Type Alkamides with NO Release Inhibitory Activities from <i>Piper puberulum</i>" @default.
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• W3152364952 doi "https://doi.org/10.1021/acs.jnatprod.1c00055" @default.
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