Matches in SemOpenAlex for { <https://semopenalex.org/work/W3153084000> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W3153084000 endingPage "944" @default.
- W3153084000 startingPage "939" @default.
- W3153084000 abstract "BACKGROUND Laryngoscopy and endotracheal intubation, a painful procedure, frequently used in airway management is commonly associated with undesired haemodynamic changes like hypertension, tachycardia and arrythmias. Thus, this study was designed to compare haemodynamic stability to laryngoscopy and intubation using single drug induction with etomidate and combined drug induction with propofol and ketamine. METHODS This was a double blind randomised controlled trial, a total of 90 patients of both sexes, aged between 18 - 60 years, who were scheduled for elective surgeries under general anaesthesia in regional institute of medical sciences (RIMS) operation theatre (OT) were divided into two groups. Group PK received propofol (1.5 mg / kg) + ketamine (0.5 mg / kg) and Group E received etomidate (0.3 mg / kg) as induction agents. The haemodynamic parameters (systolic blood pressureSBP, diastolic blood pressure-DBP, mean arterial pressure-MAP, heart rate-HR) were recorded before induction, immediately after induction, 1, 3 and 5 mins after intubation. Side effects like myoclonus and post-operative nausea and vomiting were also noted. RESULTS SBP, DBP, MAP which were recorded, before induction considered as the baseline, and after induction, were comparable between the two groups. SBP, DBP and MAP compared at 1, 3 and 5 mins after intubation showed statistically significant difference between the two groups with propofol-ketamine group showing better haemodynamic stability. The HR between both the groups at various time intervals were comparable and not considered statistically significant. The side effect associated after induction was myoclonus in 14 patients in Group E i.e. 31 % and post-operative nausea vomiting was observed in 8 patients in Group E i.e. 18 %. CONCLUSIONS Thus, in view of haemodynamic stability during laryngoscopy, intubation and side effect profile; propofol and ketamine combination proves to be a better alternative compared to etomidate according to our study. KEYWORDS Propofol, Ketamine, Etomidate, Haemodynamic Stability" @default.
- W3153084000 created "2021-04-26" @default.
- W3153084000 creator A5012851157 @default.
- W3153084000 creator A5040212938 @default.
- W3153084000 creator A5065132134 @default.
- W3153084000 creator A5068989896 @default.
- W3153084000 date "2021-04-12" @default.
- W3153084000 modified "2023-10-18" @default.
- W3153084000 title "Comparative Study of Effect of Etomidate Versus Propofol plus Ketamine on Haemodynamic Response to Laryngoscopy and Endotracheal Intubation" @default.
- W3153084000 doi "https://doi.org/10.18410/jebmh/2021/182" @default.
- W3153084000 hasPublicationYear "2021" @default.
- W3153084000 type Work @default.
- W3153084000 sameAs 3153084000 @default.
- W3153084000 citedByCount "0" @default.
- W3153084000 crossrefType "journal-article" @default.
- W3153084000 hasAuthorship W3153084000A5012851157 @default.
- W3153084000 hasAuthorship W3153084000A5040212938 @default.
- W3153084000 hasAuthorship W3153084000A5065132134 @default.
- W3153084000 hasAuthorship W3153084000A5068989896 @default.
- W3153084000 hasConcept C126322002 @default.
- W3153084000 hasConcept C178853913 @default.
- W3153084000 hasConcept C26170363 @default.
- W3153084000 hasConcept C2776277131 @default.
- W3153084000 hasConcept C2776452961 @default.
- W3153084000 hasConcept C2776888792 @default.
- W3153084000 hasConcept C2777953023 @default.
- W3153084000 hasConcept C2778716859 @default.
- W3153084000 hasConcept C2779676917 @default.
- W3153084000 hasConcept C2780580376 @default.
- W3153084000 hasConcept C2780795376 @default.
- W3153084000 hasConcept C42219234 @default.
- W3153084000 hasConcept C71924100 @default.
- W3153084000 hasConcept C84393581 @default.
- W3153084000 hasConceptScore W3153084000C126322002 @default.
- W3153084000 hasConceptScore W3153084000C178853913 @default.
- W3153084000 hasConceptScore W3153084000C26170363 @default.
- W3153084000 hasConceptScore W3153084000C2776277131 @default.
- W3153084000 hasConceptScore W3153084000C2776452961 @default.
- W3153084000 hasConceptScore W3153084000C2776888792 @default.
- W3153084000 hasConceptScore W3153084000C2777953023 @default.
- W3153084000 hasConceptScore W3153084000C2778716859 @default.
- W3153084000 hasConceptScore W3153084000C2779676917 @default.
- W3153084000 hasConceptScore W3153084000C2780580376 @default.
- W3153084000 hasConceptScore W3153084000C2780795376 @default.
- W3153084000 hasConceptScore W3153084000C42219234 @default.
- W3153084000 hasConceptScore W3153084000C71924100 @default.
- W3153084000 hasConceptScore W3153084000C84393581 @default.
- W3153084000 hasIssue "15" @default.
- W3153084000 hasLocation W31530840001 @default.
- W3153084000 hasOpenAccess W3153084000 @default.
- W3153084000 hasPrimaryLocation W31530840001 @default.
- W3153084000 hasRelatedWork W1996825671 @default.
- W3153084000 hasRelatedWork W2167497342 @default.
- W3153084000 hasRelatedWork W2206036181 @default.
- W3153084000 hasRelatedWork W2322409140 @default.
- W3153084000 hasRelatedWork W2382559217 @default.
- W3153084000 hasRelatedWork W4212956725 @default.
- W3153084000 hasRelatedWork W4312424091 @default.
- W3153084000 hasRelatedWork W79371275 @default.
- W3153084000 hasRelatedWork W2181900782 @default.
- W3153084000 hasRelatedWork W3087863961 @default.
- W3153084000 hasVolume "8" @default.
- W3153084000 isParatext "false" @default.
- W3153084000 isRetracted "false" @default.
- W3153084000 magId "3153084000" @default.
- W3153084000 workType "article" @default.