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• W3153172877 abstract "In-vivo DNA organization at large length scales ($sim 100nm$) is highly debated and polymer models have proved useful to understand the principle of DNA-organization. Here, we show that $<2$% cross-links at specific points in a ring polymer can lead to a distinct spatial organization of the polymer. The specific pairs of cross-linked monomers were extracted from contact maps of bacterial DNA. We are able to predict the structure of 2 DNAs using Monte Carlo simulations of the bead-spring polymer with cross-links at these special positions. Simulations with cross-links at random positions along the chain show that the organization of the polymer is different in nature from the previous case." @default.
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• W3153172877 date "2018-01-01" @default.
• W3153172877 modified "2023-09-24" @default.
• W3153172877 title "Origin of spatial organization of DNA-polymer in bacterial chromosomes" @default.
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• W3153172877 doi "https://doi.org/10.1209/0295-5075/121/18004" @default.
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