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- W3153300510 abstract "The increasing rate of antimicrobial resistance (AMR) in pathogenic bacteria is a global threat to human and veterinary medicine. Beyond antibiotics, antimicrobial peptides (AMPs) might be an alternative to inhibit the growth of bacteria, including AMR pathogens, on different surfaces. Biofilm formation, which starts out as bacterial adhesion, poses additional challenges for antibiotics targeting bacterial cells. The objective of this study was to establish a real-time method for the monitoring of the inhibition of (a) bacterial adhesion to a defined substrate and (b) biofilm formation by AMPs using an innovative thermal sensor. We provide evidence that the thermal sensor enables continuous monitoring of the effect of two potent AMPs, protamine and OH-CATH-30, on surface colonization of bovine mastitis-associated Escherichia (E.) coli and Staphylococcus (S.) aureus. The bacteria were grown under static conditions on the surface of the sensor membrane, on which temperature oscillations generated by a heater structure were detected by an amorphous germanium thermistor. Bacterial adhesion, which was confirmed by white light interferometry, caused a detectable amplitude change and phase shift. To our knowledge, the thermal measurement system has never been used to assess the effect of AMPs on bacterial adhesion in real time before. The system could be used to screen and evaluate bacterial adhesion inhibition of both known and novel AMPs." @default.
- W3153300510 created "2021-04-26" @default.
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- W3153300510 date "2021-04-14" @default.
- W3153300510 modified "2023-10-16" @default.
- W3153300510 title "A Real-Time Thermal Sensor System for Quantifying the Inhibitory Effect of Antimicrobial Peptides on Bacterial Adhesion and Biofilm Formation" @default.
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- W3153300510 cites W1992663677 @default.
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- W3153300510 cites W2005328241 @default.
- W3153300510 cites W2008762743 @default.
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- W3153300510 cites W2021283241 @default.
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- W3153300510 cites W2040975493 @default.
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- W3153300510 cites W2562261325 @default.
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- W3153300510 cites W2637225027 @default.
- W3153300510 cites W2761783016 @default.
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- W3153300510 doi "https://doi.org/10.3390/s21082771" @default.
- W3153300510 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8070953" @default.
- W3153300510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33919962" @default.
- W3153300510 hasPublicationYear "2021" @default.
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