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- W3153425243 abstract "Progressive multifocal leucoencephalopathy is a serious side effect of natalizumab, a humanized monoclonal antibody approved for the treatment of multiple sclerosis. Here, we report a case of unexpected worsening of natalizumab-related progressive multifocal leucoencephalopathy following COVID-19. After natalizumab discontinuation, a slight neurological improvement was observed, but, two months later the patient was admitted to the hospital because of neurological deterioration and COVID-19 mild pneumonia. Except for SARS-CoV-2 infection, no other potential factors of neurological worsening were identified. Thus, we pose the hypothesis that SARS-CoV-2 was instrumental in the progressive multifocal leucoencephalopathy deterioration." @default.
- W3153425243 created "2021-04-26" @default.
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- W3153425243 date "2021-04-19" @default.
- W3153425243 modified "2023-09-26" @default.
- W3153425243 title "Unexpected worsening of progressive multifocal leucoencephalopathy following COVID-19 pneumonia" @default.
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- W3153425243 doi "https://doi.org/10.1007/s13365-021-00980-2" @default.
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