FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3153603904> ?p ?o ?g. }

• W3153603904 endingPage "e0249954" @default.
• W3153603904 startingPage "e0249954" @default.
• W3153603904 abstract "Cells have a regulatory mechanism known as heat shock (HS) response, which induces the expression of HS genes and proteins in response to heat and other cellular stresses. Exposure to moderate HS results in beneficial effects, such as thermotolerance and promotes survival, whereas excessive HS causes cell death. The effect of HS on cells depends on both exogenous factors, including the temperature and duration of heat application, and endogenous factors, such as the degree of cell differentiation. Neural stem cells (NSCs) can self-renew and differentiate into neurons and glial cells, but the changes in the HS response of symmetrically proliferating NSCs in culture are unclear. We evaluated the HS response of homogeneous proliferating NSCs derived from mouse embryonic stem cells during the proliferative phase and its effect on survival and cell death in vitro . The number of adherent cells and the expression ratios of HS protein ( Hsp ) 40 and Hsp70 genes after exposure to HS for 20 min at temperatures above 43°C significantly increased with the extension of the culture period before exposure to HS. In contrast, caspase activity was significantly decreased by extension of the culture period before exposure to HS and suppressed the decrease in cell viability. These results suggest that the culture period before HS remarkably affects the HS response, influencing the expression of HS genes and cell survival of proliferating NSCs in culture." @default.
• W3153603904 created "2021-04-26" @default.
• W3153603904 creator A5031969792 @default.
• W3153603904 creator A5083135332 @default.
• W3153603904 creator A5086333618 @default.
• W3153603904 creator A5090756574 @default.
• W3153603904 date "2021-04-14" @default.
• W3153603904 modified "2023-10-18" @default.
• W3153603904 title "Heat shock response enhanced by cell culture treatment in mouse embryonic stem cell-derived proliferating neural stem cells" @default.
• W3153603904 cites W118409790 @default.
• W3153603904 cites W1481393636 @default.
• W3153603904 cites W1515506492 @default.
• W3153603904 cites W1607384859 @default.
• W3153603904 cites W1643680178 @default.
• W3153603904 cites W1652680663 @default.
• W3153603904 cites W1956857446 @default.
• W3153603904 cites W1963770237 @default.
• W3153603904 cites W1964136810 @default.
• W3153603904 cites W1966476278 @default.
• W3153603904 cites W1967870335 @default.
• W3153603904 cites W1970774026 @default.
• W3153603904 cites W1972980743 @default.
• W3153603904 cites W1973359552 @default.
• W3153603904 cites W1976571103 @default.
• W3153603904 cites W1976854735 @default.
• W3153603904 cites W2001858086 @default.
• W3153603904 cites W2005790733 @default.
• W3153603904 cites W2011265783 @default.
• W3153603904 cites W2014147440 @default.
• W3153603904 cites W2018673123 @default.
• W3153603904 cites W2027449023 @default.
• W3153603904 cites W2027688801 @default.
• W3153603904 cites W2035531438 @default.
• W3153603904 cites W2044887893 @default.
• W3153603904 cites W2056331991 @default.
• W3153603904 cites W2057641653 @default.
• W3153603904 cites W2058396021 @default.
• W3153603904 cites W2067043257 @default.
• W3153603904 cites W2075612514 @default.
• W3153603904 cites W2076439643 @default.
• W3153603904 cites W2079356804 @default.
• W3153603904 cites W2083814453 @default.
• W3153603904 cites W2084652820 @default.
• W3153603904 cites W2087786585 @default.
• W3153603904 cites W2089227826 @default.
• W3153603904 cites W2092713508 @default.
• W3153603904 cites W2094164804 @default.
• W3153603904 cites W2096713885 @default.
• W3153603904 cites W2106483894 @default.
• W3153603904 cites W2107789276 @default.
• W3153603904 cites W2113210947 @default.
• W3153603904 cites W2132643489 @default.
• W3153603904 cites W2137417707 @default.
• W3153603904 cites W2139196095 @default.
• W3153603904 cites W2146779753 @default.
• W3153603904 cites W2148927308 @default.
• W3153603904 cites W2151013318 @default.
• W3153603904 cites W2156110752 @default.
• W3153603904 cites W2168601768 @default.
• W3153603904 cites W2210469066 @default.
• W3153603904 cites W2394564854 @default.
• W3153603904 cites W2755186712 @default.
• W3153603904 cites W2779970637 @default.
• W3153603904 cites W2783912179 @default.
• W3153603904 doi "https://doi.org/10.1371/journal.pone.0249954" @default.
• W3153603904 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8046196" @default.
• W3153603904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33852623" @default.
• W3153603904 hasPublicationYear "2021" @default.
• W3153603904 type Work @default.
• W3153603904 sameAs 3153603904 @default.
• W3153603904 citedByCount "5" @default.
• W3153603904 countsByYear W31536039042021 @default.
• W3153603904 countsByYear W31536039042022 @default.
• W3153603904 countsByYear W31536039042023 @default.
• W3153603904 crossrefType "journal-article" @default.
• W3153603904 hasAuthorship W3153603904A5031969792 @default.
• W3153603904 hasAuthorship W3153603904A5083135332 @default.
• W3153603904 hasAuthorship W3153603904A5086333618 @default.
• W3153603904 hasAuthorship W3153603904A5090756574 @default.
• W3153603904 hasBestOaLocation W31536039041 @default.
• W3153603904 hasConcept C104317684 @default.
• W3153603904 hasConcept C136834591 @default.
• W3153603904 hasConcept C137984847 @default.
• W3153603904 hasConcept C145103041 @default.
• W3153603904 hasConcept C148738053 @default.
• W3153603904 hasConcept C153911025 @default.
• W3153603904 hasConcept C162746124 @default.
• W3153603904 hasConcept C190283241 @default.
• W3153603904 hasConcept C205260736 @default.
• W3153603904 hasConcept C20875687 @default.
• W3153603904 hasConcept C28328180 @default.
• W3153603904 hasConcept C31573885 @default.
• W3153603904 hasConcept C53227056 @default.
• W3153603904 hasConcept C54355233 @default.
• W3153603904 hasConcept C68991219 @default.
• W3153603904 hasConcept C81885089 @default.
• W3153603904 hasConcept C86803240 @default.
• W3153603904 hasConcept C95444343 @default.

• next