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• W3153697029 abstract "To investigate demographics and causes of pediatric uveitis in a Swiss tertiary reference center over a 20-year period.Retrospective cohort study on patients with uveitis aged less than 16 years seen at Jules-Gonin Eye Hospital between 1 January 2000 and 31 December 2019.Out of 2846 patients with uveitis seen in the Jules-Gonin Eye Hospital Ocular Immune-Infectiology Department, 317 (11.1%) were under 16 years of age and were included in this study. Median age at onset of the uveitis was 8.9 years (range 0 - 16). Anterior uveitis was the most frequent presentation (45.1%) followed by posterior uveitis in 26.2%, intermediate uveitis in 23.3%, and panuveitis in 5.4%. The inflammation was most frequently bilateral and non-granulomatous. A systemic inflammatory disease was found in 34% of the cases and an infectious cause in 24%.The repartition of the location of the uveitis was similar to previous reports from Western countries. Uveitis in juvenile idiopathic arthritis is the most frequent etiology related to a systemic disease in children. An infectious cause was found in 24% of our patients, which is a greater proportion than in adult cohorts.Die Studie untersucht die Demografie und Ätiologie der Kindheitsuveitis über eine 20-Jahres-Periode in einem Universitätsspital.Diese Studie hat Kinder unter 16 Jahren eingeschlossen, die zwischen dem 1. Januar 2000 und dem 31. Dezember 2019 im Jules Gonin Augenspital auf eine Uveitis untersucht worden sind. Die Daten wurden retrospektiv analysiert.2846 Patienten mit Uveitis wurden untersucht und 317 (11,1%) davon waren Kinder. Das mediane Alter des Krankheitsbeginns war 8,9 Jahre (Range 0 – 16). Die anatomische Lokalisation war am häufigsten anterior (45,1%). Dann folgten die posteriore (26,2%) und die intermediäre (23,3%) Uveitis. Die Panuveitis war mit 5,4% am seltensten vorhanden. Die Entzündung war am häufigsten bilateral und nicht granulomatös. Eine systemische Immunerkrankung wurde in 34% der Fälle entdeckt und 24% der Kinder hatten eine infektiöse Ursache der Uveitis.Die Aufteilung der anatomischen Lokalisation war vergleichbar zu epidemiologischen Studien der 20 früheren Jahre. Die juvenile idiopathische Arthritis ist immer noch die häufigste Ursache für eine Uveitis in der Kindheit. Eine infektiöse Ursache wurde in fast einem Viertel der Fälle gefunden, was verhältnismäßig häufiger ist als bei Erwachsenen." @default.
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• W3153697029 date "2021-04-01" @default.
• W3153697029 modified "2023-09-27" @default.
• W3153697029 title "Epidemiology of Childhood Uveitis in a Tertiary Care Center: A 20-Year Study" @default.
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• W3153697029 doi "https://doi.org/10.1055/a-1384-0351" @default.
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