Matches in SemOpenAlex for { <https://semopenalex.org/work/W3153872847> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W3153872847 endingPage "2619" @default.
- W3153872847 startingPage "2612" @default.
- W3153872847 abstract "Efficient and targeted screening and isolation of bioactive compounds from complex natural products is still a challenging work. Herein, diagnostic ion filtering based high-performance liquid chromatography-quadrupole time-of-flight-tandem mass spectrometry was firstly developed to screen six main iridoid glycosides from Hedyotis diffusa. Then, online extraction-high-speed counter current chromatography was proposed for targeted enrichment and preparative isolation using ethyl acetate/n-butanol/water (4.5:0.5:5, v/v/v) as solvent system. After that, Sephadex LH-20 column chromatography using methanol as solvent system was selected for further purification of six iridoid glycosides with purities over 98%. They were finally identified as monotropein, desacetylasperuloside acid, asperuloside, 6-O-(Z)-p-coumaroyl scandoside methyl ester, 6-O-(Z)-feruloyl scandoside methyl ester, and 6-O-(E)-p-coumaroyl scandoside methyl ester. And their anti-inflammatory activities were evaluated and confirmed by lipopolysaccharide activated RAW 264.7 macrophages. Obviously, the results provide a scientific basis for the potential applications of H. diffusa, and the developed methodology is efficient and reliable for targeted screening and isolation of bioactive compounds from natural products." @default.
- W3153872847 created "2021-04-26" @default.
- W3153872847 creator A5006068787 @default.
- W3153872847 creator A5021235057 @default.
- W3153872847 creator A5028093999 @default.
- W3153872847 creator A5036822473 @default.
- W3153872847 creator A5050415417 @default.
- W3153872847 creator A5069133267 @default.
- W3153872847 date "2021-05-26" @default.
- W3153872847 modified "2023-10-09" @default.
- W3153872847 title "Diagnostic ion filtering targeted screening and isolation of anti‐inflammatory iridoid glycosides from <i>Hedyotis diffusa</i>" @default.
- W3153872847 cites W1968306744 @default.
- W3153872847 cites W1981445087 @default.
- W3153872847 cites W2007056184 @default.
- W3153872847 cites W2023301636 @default.
- W3153872847 cites W2040790475 @default.
- W3153872847 cites W2066968176 @default.
- W3153872847 cites W2168335449 @default.
- W3153872847 cites W2401009689 @default.
- W3153872847 cites W2782555529 @default.
- W3153872847 cites W2791258558 @default.
- W3153872847 cites W2811490671 @default.
- W3153872847 cites W2818585431 @default.
- W3153872847 cites W2886278858 @default.
- W3153872847 cites W2946451821 @default.
- W3153872847 cites W2966424861 @default.
- W3153872847 cites W2972688476 @default.
- W3153872847 cites W2979518442 @default.
- W3153872847 cites W2989568092 @default.
- W3153872847 cites W2992091214 @default.
- W3153872847 cites W2996381272 @default.
- W3153872847 cites W3003719351 @default.
- W3153872847 cites W3012437703 @default.
- W3153872847 cites W3017090987 @default.
- W3153872847 cites W3017587445 @default.
- W3153872847 cites W3022617143 @default.
- W3153872847 cites W3036848246 @default.
- W3153872847 cites W3041439148 @default.
- W3153872847 cites W2986026696 @default.
- W3153872847 doi "https://doi.org/10.1002/jssc.202100074" @default.
- W3153872847 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33884739" @default.
- W3153872847 hasPublicationYear "2021" @default.
- W3153872847 type Work @default.
- W3153872847 sameAs 3153872847 @default.
- W3153872847 citedByCount "8" @default.
- W3153872847 countsByYear W31538728472021 @default.
- W3153872847 countsByYear W31538728472022 @default.
- W3153872847 countsByYear W31538728472023 @default.
- W3153872847 crossrefType "journal-article" @default.
- W3153872847 hasAuthorship W3153872847A5006068787 @default.
- W3153872847 hasAuthorship W3153872847A5021235057 @default.
- W3153872847 hasAuthorship W3153872847A5028093999 @default.
- W3153872847 hasAuthorship W3153872847A5036822473 @default.
- W3153872847 hasAuthorship W3153872847A5050415417 @default.
- W3153872847 hasAuthorship W3153872847A5069133267 @default.
- W3153872847 hasConcept C178790620 @default.
- W3153872847 hasConcept C185592680 @default.
- W3153872847 hasConcept C194671627 @default.
- W3153872847 hasConcept C2778413156 @default.
- W3153872847 hasConcept C2779858419 @default.
- W3153872847 hasConcept C2780471494 @default.
- W3153872847 hasConcept C43617362 @default.
- W3153872847 hasConcept C51724486 @default.
- W3153872847 hasConceptScore W3153872847C178790620 @default.
- W3153872847 hasConceptScore W3153872847C185592680 @default.
- W3153872847 hasConceptScore W3153872847C194671627 @default.
- W3153872847 hasConceptScore W3153872847C2778413156 @default.
- W3153872847 hasConceptScore W3153872847C2779858419 @default.
- W3153872847 hasConceptScore W3153872847C2780471494 @default.
- W3153872847 hasConceptScore W3153872847C43617362 @default.
- W3153872847 hasConceptScore W3153872847C51724486 @default.
- W3153872847 hasIssue "13" @default.
- W3153872847 hasLocation W31538728471 @default.
- W3153872847 hasLocation W31538728472 @default.
- W3153872847 hasOpenAccess W3153872847 @default.
- W3153872847 hasPrimaryLocation W31538728471 @default.
- W3153872847 hasRelatedWork W1957242906 @default.
- W3153872847 hasRelatedWork W2004708620 @default.
- W3153872847 hasRelatedWork W2012439544 @default.
- W3153872847 hasRelatedWork W2209470164 @default.
- W3153872847 hasRelatedWork W2347873383 @default.
- W3153872847 hasRelatedWork W2356920129 @default.
- W3153872847 hasRelatedWork W2380056494 @default.
- W3153872847 hasRelatedWork W2519545220 @default.
- W3153872847 hasRelatedWork W2794462520 @default.
- W3153872847 hasRelatedWork W2928313023 @default.
- W3153872847 hasVolume "44" @default.
- W3153872847 isParatext "false" @default.
- W3153872847 isRetracted "false" @default.
- W3153872847 magId "3153872847" @default.
- W3153872847 workType "article" @default.