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- W3153999743 abstract "Summary When monocytes migrate from blood into tissues they differentiate into macrophage‐like cells. The outcome of this differentiation process is strongly influenced by the tissue environment, and the macrophages produced help control the immunological properties of the tissue. The process of monocyte–macrophage differentiation is therefore potentially attractive when seeking therapeutic targets to amplify or modulate the inflammatory response. Here we highlight recent research in this area, identifying the gene Paqr11 as an important factor in monocyte differentiation, and therefore an important potential target for reducing macrophage‐mediated inflammation in arthritis." @default.
- W3153999743 created "2021-04-26" @default.
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- W3153999743 date "2021-04-13" @default.
- W3153999743 modified "2023-10-17" @default.
- W3153999743 title "Can we treat inflammation by managing misbehaving monocytes?" @default.
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- W3153999743 doi "https://doi.org/10.1111/imm.13334" @default.
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