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• W3154017842 endingPage "20200123" @default.
• W3154017842 startingPage "20200123" @default.
• W3154017842 abstract "DNA provides the fundamental framework for heritability, yet heritable trait variation need not be completely 'hard-wired' into the DNA sequence. In plants, the epigenetic machinery that controls transposable element (TE) activity, and which includes DNA methylation, underpins most known cases of inherited trait variants that are independent of DNA sequence changes. Here, we review our current knowledge of the extent, mechanisms and potential adaptive contribution of epiallelic variation at TE-containing alleles in this group of species. For the purpose of this review, we focus mainly on DNA methylation, as it provides an easily quantifiable readout of such variation. The picture that emerges is complex. On the one hand, pronounced differences in DNA methylation at TE sequences can either occur spontaneously or be induced experimentally en masse across the genome through genetic means. Many of these epivariants are stably inherited over multiple sexual generations, thus leading to transgenerational epigenetic inheritance. Functional consequences can be significant, yet they are typically of limited magnitude and although the same epivariants can be found in nature, the factors involved in their generation in this setting remain to be determined. On the other hand, moderate DNA methylation variation at TE-containing alleles can be reproducibly induced by the environment, again usually with mild effects, and most of this variation tends to be lost across generations. Based on these considerations, we argue that TE-containing alleles, rather than their inherited epiallelic variants, are the main targets of natural selection. Thus, we propose that the adaptive contribution of TE-associated epivariation, whether stable or not, lies predominantly in its capacity to modulate TE mobilization in response to the environment, hence providing hard-wired opportunities for the flexible exploration of the phenotypic space. This article is part of the theme issue 'How does epigenetics influence the course of evolution?'" @default.
• W3154017842 created "2021-04-26" @default.
• W3154017842 creator A5014837588 @default.
• W3154017842 creator A5053603420 @default.
• W3154017842 date "2021-04-19" @default.
• W3154017842 modified "2023-10-11" @default.
• W3154017842 title "The epiallelic potential of transposable elements and its evolutionary significance in plants" @default.
• W3154017842 cites W1413417492 @default.
• W3154017842 cites W1560609485 @default.
• W3154017842 cites W1562691460 @default.
• W3154017842 cites W1757110396 @default.
• W3154017842 cites W1843081542 @default.
• W3154017842 cites W1967817540 @default.
• W3154017842 cites W1977588103 @default.
• W3154017842 cites W1978683904 @default.
• W3154017842 cites W1980436308 @default.
• W3154017842 cites W1981669094 @default.
• W3154017842 cites W1984891757 @default.
• W3154017842 cites W1987104387 @default.
• W3154017842 cites W1988935841 @default.
• W3154017842 cites W1990513713 @default.
• W3154017842 cites W1998918762 @default.
• W3154017842 cites W2002128513 @default.
• W3154017842 cites W2003623249 @default.
• W3154017842 cites W2009842501 @default.
• W3154017842 cites W2014299430 @default.
• W3154017842 cites W2015305713 @default.
• W3154017842 cites W2016813268 @default.
• W3154017842 cites W2017198614 @default.
• W3154017842 cites W2019613936 @default.
• W3154017842 cites W2026343134 @default.
• W3154017842 cites W2028839461 @default.
• W3154017842 cites W2030819518 @default.
• W3154017842 cites W2031225004 @default.
• W3154017842 cites W2031913559 @default.
• W3154017842 cites W2036693641 @default.
• W3154017842 cites W2037928358 @default.
• W3154017842 cites W2039729902 @default.
• W3154017842 cites W2043233868 @default.
• W3154017842 cites W2043487490 @default.
• W3154017842 cites W2044231545 @default.
• W3154017842 cites W2046584121 @default.
• W3154017842 cites W2046942607 @default.
• W3154017842 cites W2049608531 @default.
• W3154017842 cites W2052639867 @default.
• W3154017842 cites W2054854463 @default.
• W3154017842 cites W2056573937 @default.
• W3154017842 cites W2058446949 @default.
• W3154017842 cites W2069680549 @default.
• W3154017842 cites W2071071826 @default.
• W3154017842 cites W2071806650 @default.
• W3154017842 cites W2072791837 @default.
• W3154017842 cites W2076498407 @default.
• W3154017842 cites W2082694471 @default.
• W3154017842 cites W2086620903 @default.
• W3154017842 cites W2087001560 @default.
• W3154017842 cites W2088616483 @default.
• W3154017842 cites W2091722627 @default.
• W3154017842 cites W2095750709 @default.
• W3154017842 cites W2107030632 @default.
• W3154017842 cites W2107289345 @default.
• W3154017842 cites W2114738891 @default.
• W3154017842 cites W2115042004 @default.
• W3154017842 cites W2117321004 @default.
• W3154017842 cites W2122241754 @default.
• W3154017842 cites W2122711136 @default.
• W3154017842 cites W2123430325 @default.
• W3154017842 cites W2125882095 @default.
• W3154017842 cites W2128023973 @default.
• W3154017842 cites W2128530971 @default.
• W3154017842 cites W2128778006 @default.
• W3154017842 cites W2130535352 @default.
• W3154017842 cites W2131473679 @default.
• W3154017842 cites W2131958646 @default.
• W3154017842 cites W2132631362 @default.
• W3154017842 cites W2133388879 @default.
• W3154017842 cites W2134216098 @default.
• W3154017842 cites W2134259729 @default.
• W3154017842 cites W2136846696 @default.
• W3154017842 cites W2137455182 @default.
• W3154017842 cites W2139288600 @default.
• W3154017842 cites W2141275463 @default.
• W3154017842 cites W2141887265 @default.
• W3154017842 cites W2147465115 @default.
• W3154017842 cites W2148565377 @default.
• W3154017842 cites W2154018910 @default.
• W3154017842 cites W2155020101 @default.
• W3154017842 cites W2156183792 @default.
• W3154017842 cites W2161148315 @default.
• W3154017842 cites W2163250539 @default.
• W3154017842 cites W2166545133 @default.
• W3154017842 cites W2167565370 @default.
• W3154017842 cites W2168031748 @default.
• W3154017842 cites W2169448038 @default.
• W3154017842 cites W2203577599 @default.
• W3154017842 cites W2290697278 @default.
• W3154017842 cites W2294638722 @default.
• W3154017842 cites W2302314933 @default.

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