FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3154543195> ?p ?o ?g. }

• W3154543195 endingPage "14" @default.
• W3154543195 startingPage "1" @default.
• W3154543195 abstract "Characterization of brain tumours requires neuropathological expertise and is generally performed by histological evaluation and molecular analysis. One emerging technique to assist pathologists in future tumour diagnostics is multimodal optical spectroscopy. In the current clinical routine, tissue preprocessing with formalin is widely established and suitable for spectroscopic investigations since degradation processes impede the measurement of native tissue. However, formalin fixation results in alterations of the tissue chemistry and morphology for example by protein cross-linking. As optical spectroscopy is sensitive to these variations, we evaluate the effects of formalin fixation on multimodal brain tumour data in this proof-of-concept study. Nonfixed and formalin-fixed cross sections of different common human brain tumours were subjected to analysis of chemical variations using ultraviolet and Fourier-transform infrared microspectroscopy. Morphological changes were assessed by elastic light scattering microspectroscopy in the visible wavelength range. Data were analysed with multivariate data analysis and compared with histopathology. Tissue type classifications deduced by optical spectroscopy are highly comparable and independent from the preparation and the fixation protocol. However, formalin fixation leads to slightly better classification models due to improved stability of the tissue. As a consequence, spectroscopic methods represent an appropriate additional contrast for chemical and morphological information in neuropathological diagnosis and should be investigated to a greater extent. Furthermore, they can be included in the clinical workflow even after formalin fixation." @default.
• W3154543195 created "2021-04-26" @default.
• W3154543195 creator A5027241562 @default.
• W3154543195 creator A5030350728 @default.
• W3154543195 creator A5030845336 @default.
• W3154543195 creator A5032205810 @default.
• W3154543195 creator A5033122338 @default.
• W3154543195 creator A5033443469 @default.
• W3154543195 creator A5038234303 @default.
• W3154543195 creator A5040991417 @default.
• W3154543195 creator A5041798640 @default.
• W3154543195 creator A5044195004 @default.
• W3154543195 creator A5052433668 @default.
• W3154543195 creator A5071373700 @default.
• W3154543195 creator A5077353204 @default.
• W3154543195 creator A5088517682 @default.
• W3154543195 creator A5090639618 @default.
• W3154543195 creator A5090717297 @default.
• W3154543195 date "2021-04-12" @default.
• W3154543195 modified "2023-10-11" @default.
• W3154543195 title "Formalin Fixation as Tissue Preprocessing for Multimodal Optical Spectroscopy Using the Example of Human Brain Tumour Cross Sections" @default.
• W3154543195 cites W1242607330 @default.
• W3154543195 cites W1548827537 @default.
• W3154543195 cites W160223114 @default.
• W3154543195 cites W1970349598 @default.
• W3154543195 cites W1974578380 @default.
• W3154543195 cites W2006139991 @default.
• W3154543195 cites W2013285062 @default.
• W3154543195 cites W2018832912 @default.
• W3154543195 cites W2025081143 @default.
• W3154543195 cites W2034180958 @default.
• W3154543195 cites W2036920132 @default.
• W3154543195 cites W2038707973 @default.
• W3154543195 cites W2045491771 @default.
• W3154543195 cites W2048778471 @default.
• W3154543195 cites W2055664824 @default.
• W3154543195 cites W2064359917 @default.
• W3154543195 cites W2068431567 @default.
• W3154543195 cites W2072128470 @default.
• W3154543195 cites W2078132525 @default.
• W3154543195 cites W2083522386 @default.
• W3154543195 cites W2088369868 @default.
• W3154543195 cites W2089468765 @default.
• W3154543195 cites W2093389480 @default.
• W3154543195 cites W2096906555 @default.
• W3154543195 cites W2111251829 @default.
• W3154543195 cites W2118425778 @default.
• W3154543195 cites W2126507993 @default.
• W3154543195 cites W2128728535 @default.
• W3154543195 cites W2137875054 @default.
• W3154543195 cites W2148091537 @default.
• W3154543195 cites W2150796457 @default.
• W3154543195 cites W2156330848 @default.
• W3154543195 cites W2160340382 @default.
• W3154543195 cites W2160382843 @default.
• W3154543195 cites W2160797083 @default.
• W3154543195 cites W2161183734 @default.
• W3154543195 cites W2169090558 @default.
• W3154543195 cites W2171177786 @default.
• W3154543195 cites W2339913352 @default.
• W3154543195 cites W2366536035 @default.
• W3154543195 cites W2410198526 @default.
• W3154543195 cites W2494489458 @default.
• W3154543195 cites W2505522325 @default.
• W3154543195 cites W2531379301 @default.
• W3154543195 cites W2594427841 @default.
• W3154543195 cites W2727617395 @default.
• W3154543195 cites W2754163606 @default.
• W3154543195 cites W2763148304 @default.
• W3154543195 cites W2770275914 @default.
• W3154543195 cites W2778797754 @default.
• W3154543195 cites W2795708784 @default.
• W3154543195 cites W2883588352 @default.
• W3154543195 cites W2899364646 @default.
• W3154543195 cites W2902461294 @default.
• W3154543195 cites W2903226777 @default.
• W3154543195 cites W2980788621 @default.
• W3154543195 cites W338754679 @default.
• W3154543195 cites W4249815350 @default.
• W3154543195 cites W77250173 @default.
• W3154543195 doi "https://doi.org/10.1155/2021/5598309" @default.
• W3154543195 hasPublicationYear "2021" @default.
• W3154543195 type Work @default.
• W3154543195 sameAs 3154543195 @default.
• W3154543195 citedByCount "8" @default.
• W3154543195 countsByYear W31545431952021 @default.
• W3154543195 countsByYear W31545431952022 @default.
• W3154543195 countsByYear W31545431952023 @default.
• W3154543195 crossrefType "journal-article" @default.
• W3154543195 hasAuthorship W3154543195A5027241562 @default.
• W3154543195 hasAuthorship W3154543195A5030350728 @default.
• W3154543195 hasAuthorship W3154543195A5030845336 @default.
• W3154543195 hasAuthorship W3154543195A5032205810 @default.
• W3154543195 hasAuthorship W3154543195A5033122338 @default.
• W3154543195 hasAuthorship W3154543195A5033443469 @default.
• W3154543195 hasAuthorship W3154543195A5038234303 @default.
• W3154543195 hasAuthorship W3154543195A5040991417 @default.
• W3154543195 hasAuthorship W3154543195A5041798640 @default.

• next