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• W3154651855 endingPage "111275" @default.
• W3154651855 startingPage "111275" @default.
• W3154651855 abstract "Malnutrition and vitamin deficiency are growing concerns in the clinical management of children with autism spectrum disorder (ASD). This case report presents a boy with ASD who developed vitamin A deficiency during follow-up.A 7-y-old boy had been diagnosed with ASD and developmental delay at age 18 mo. He developed convulsions associated with hypocalcemia and vitamin D deficiency at 3 y of age. Although vitamin D supplementation was continued, he was only able to eat rice, green tea, and fried potatoes from 3 y of age to age 7 y. He had started rubbing his eyes and had refused to open his eyes 9 mo before. An ophthalmologic examination showed bilateral corneal ulcers and right corneal perforation. Vitamin A was immediately supplemented with a nasogastric tube; however, his right eye was surgically enucleated against the persistent infection.A search of the relevant literature from 1993 to 2020 identified 11 cases of patients with ASD (5-17 y of age) who developed vitamin A deficiency owing to malnutrition. Only 4 cases (36%) had a full recovery in visual acuity.Vitamin A deficiency frequently causes irreversible visual impairment in children with ASD. Vigilant monitoring of vitamin levels prevents unfavorable outcomes in children with ASD and difficulty in food intake." @default.
• W3154651855 created "2021-04-26" @default.
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• W3154651855 date "2021-10-01" @default.
• W3154651855 modified "2023-10-18" @default.
• W3154651855 title "Vitamin A deficiency–associated corneal perforation in a boy with autism spectrum disorder: A case report and literature review" @default.
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• W3154651855 doi "https://doi.org/10.1016/j.nut.2021.111275" @default.
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