FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3154758538> ?p ?o ?g. }

• W3154758538 abstract "Early identification of glioma molecular phenotypes can lead to understanding of patient prognosis and treatment guidance. We aimed to develop a multiparametric MRI texture analysis model using a combination of conventional and diffusion MRI to predict a wide range of biomarkers in patients with glioma.In this retrospective study, patients were included if they (1) had diagnosis of gliomas with known IDH1, EGFR, MGMT, ATRX, TP53, and PTEN status from surgical pathology and (2) had preoperative MRI including FLAIR, T1c+ and diffusion for radiomic texture analysis. Statistical analysis included logistic regression and receiver-operating characteristic (ROC) curve analysis to determine the optimal model for predicting glioma biomarkers. A comparative analysis between ROCs (conventional only vs conventional + diffusion) was performed.From a total of 111 patients included, 91 (82%) were categorized to training and 20 (18%) to test datasets. Constructed cross-validated model using a combination of texture features from conventional and diffusion MRI resulted in overall AUC/accuracy of 1/79% for IDH1, 0.99/80% for ATRX, 0.79/67% for MGMT, and 0.77/66% for EGFR. The addition of diffusion data to conventional MRI features significantly (P < .05) increased predictive performance for IDH1, MGMT, and ATRX. The overall accuracy of the final model in predicting biomarkers in the test group was 80% (IDH1), 70% (ATRX), 70% (MGMT), and 75% (EGFR).Addition of MR diffusion to conventional MRI features provides added diagnostic value in preoperative determination of IDH1, MGMT, and ATRX in patients with glioma." @default.
• W3154758538 created "2021-04-26" @default.
• W3154758538 creator A5017671349 @default.
• W3154758538 creator A5020416052 @default.
• W3154758538 creator A5023354062 @default.
• W3154758538 creator A5040894533 @default.
• W3154758538 creator A5048249806 @default.
• W3154758538 creator A5052154203 @default.
• W3154758538 creator A5061870462 @default.
• W3154758538 creator A5067278624 @default.
• W3154758538 creator A5068394714 @default.
• W3154758538 creator A5087652932 @default.
• W3154758538 creator A5088994182 @default.
• W3154758538 date "2021-01-01" @default.
• W3154758538 modified "2023-10-13" @default.
• W3154758538 title "Multiparametric MRI texture analysis in prediction of glioma biomarker status: added value of MR diffusion" @default.
• W3154758538 cites W1812256879 @default.
• W3154758538 cites W1994233351 @default.
• W3154758538 cites W2019090719 @default.
• W3154758538 cites W2033973189 @default.
• W3154758538 cites W2041623103 @default.
• W3154758538 cites W2044465660 @default.
• W3154758538 cites W2048281021 @default.
• W3154758538 cites W2071970335 @default.
• W3154758538 cites W2074179372 @default.
• W3154758538 cites W2096287682 @default.
• W3154758538 cites W2109816625 @default.
• W3154758538 cites W2111229057 @default.
• W3154758538 cites W2115276344 @default.
• W3154758538 cites W2121749405 @default.
• W3154758538 cites W2136734008 @default.
• W3154758538 cites W2159842626 @default.
• W3154758538 cites W2161289668 @default.
• W3154758538 cites W2320688130 @default.
• W3154758538 cites W2328176404 @default.
• W3154758538 cites W2367516440 @default.
• W3154758538 cites W2460821456 @default.
• W3154758538 cites W2460918282 @default.
• W3154758538 cites W2465688795 @default.
• W3154758538 cites W2519238003 @default.
• W3154758538 cites W2592397787 @default.
• W3154758538 cites W2610646966 @default.
• W3154758538 cites W2741586856 @default.
• W3154758538 cites W2761786032 @default.
• W3154758538 cites W2781200392 @default.
• W3154758538 cites W2787262857 @default.
• W3154758538 cites W2793653887 @default.
• W3154758538 cites W2892163151 @default.
• W3154758538 cites W2901372644 @default.
• W3154758538 cites W2911331066 @default.
• W3154758538 cites W2911798414 @default.
• W3154758538 cites W2937084457 @default.
• W3154758538 cites W2945478270 @default.
• W3154758538 cites W2951525397 @default.
• W3154758538 cites W3002676507 @default.
• W3154758538 cites W3095170425 @default.
• W3154758538 doi "https://doi.org/10.1093/noajnl/vdab051" @default.
• W3154758538 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8156980" @default.
• W3154758538 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34056604" @default.
• W3154758538 hasPublicationYear "2021" @default.
• W3154758538 type Work @default.
• W3154758538 sameAs 3154758538 @default.
• W3154758538 citedByCount "15" @default.
• W3154758538 countsByYear W31547585382021 @default.
• W3154758538 countsByYear W31547585382022 @default.
• W3154758538 countsByYear W31547585382023 @default.
• W3154758538 crossrefType "journal-article" @default.
• W3154758538 hasAuthorship W3154758538A5017671349 @default.
• W3154758538 hasAuthorship W3154758538A5020416052 @default.
• W3154758538 hasAuthorship W3154758538A5023354062 @default.
• W3154758538 hasAuthorship W3154758538A5040894533 @default.
• W3154758538 hasAuthorship W3154758538A5048249806 @default.
• W3154758538 hasAuthorship W3154758538A5052154203 @default.
• W3154758538 hasAuthorship W3154758538A5061870462 @default.
• W3154758538 hasAuthorship W3154758538A5067278624 @default.
• W3154758538 hasAuthorship W3154758538A5068394714 @default.
• W3154758538 hasAuthorship W3154758538A5087652932 @default.
• W3154758538 hasAuthorship W3154758538A5088994182 @default.
• W3154758538 hasBestOaLocation W31547585381 @default.
• W3154758538 hasConcept C101070640 @default.
• W3154758538 hasConcept C104317684 @default.
• W3154758538 hasConcept C126322002 @default.
• W3154758538 hasConcept C126838900 @default.
• W3154758538 hasConcept C127848430 @default.
• W3154758538 hasConcept C143409427 @default.
• W3154758538 hasConcept C143998085 @default.
• W3154758538 hasConcept C149550507 @default.
• W3154758538 hasConcept C151956035 @default.
• W3154758538 hasConcept C2776689207 @default.
• W3154758538 hasConcept C2778227246 @default.
• W3154758538 hasConcept C2781197716 @default.
• W3154758538 hasConcept C2989005 @default.
• W3154758538 hasConcept C45664433 @default.
• W3154758538 hasConcept C501734568 @default.
• W3154758538 hasConcept C502942594 @default.
• W3154758538 hasConcept C55493867 @default.
• W3154758538 hasConcept C58471807 @default.
• W3154758538 hasConcept C70816921 @default.
• W3154758538 hasConcept C71924100 @default.
• W3154758538 hasConcept C76318530 @default.

• next