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- W3154777281 abstract "Purpose: It is now commonly accepted that cartilage and bone pathology are strongly associated in osteoarthritis (OA) initiation and progression, and it is therefore of great importance to understand the molecular changes in the osteochondral unit. Protein extraction from cartilage and subchondral bone samples is challenging and most techniques used so far often cause selective loss of groups of proteins and relatively low protein yield. In this study, we used two workflows based on either pressure cycling technology (PCT) or ultrasonication (US) in combination with data independent acquisition (DIA) based mass spectrometry (MS) analysis to quantitatively assess the proteomes of articular cartilage and subchondral bone." @default.
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- W3154777281 date "2021-04-01" @default.
- W3154777281 modified "2023-10-16" @default.
- W3154777281 title "A comprehensive and quantifiable insight into the proteomes of articular cartilage and subchondral bone" @default.
- W3154777281 doi "https://doi.org/10.1016/j.joca.2021.02.176" @default.
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