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• W3155231617 abstract "The albumin-bilirubin (ALBI) grade has been validated as a significant prognostic predictor for hepatocellular carcinoma (HCC). However, there is little information about the ALBI grade in patients with non-B non-C HCC (NBNC-HCC) receiving surgery.This study aimed to evaluate the prognostic significance of the ALBI grade in patients with NBNC-HCC after primary curative resection.From January 2010 to April 2016, 2137 patients with HCC who received hepatectomy were screened for study eligibility. Finally, a total of 168 NBNC-HCC patients who received primary curative resection were analyzed. The impacts of the ALBI grade on disease-free survival (DFS) and overall survival (OS) were analyzed by multivariate analysis.There were 66 (39.3%), 98 (58.3%), and 4 (2.4%) patients with an ALBI grade of I, II, and III, respectively. Patients with an ALBI grade II/III were older (p = 0.002), more likely to have hypoalbuminemia (p < 0.001), and more commonly had Child-Pugh class B (p = 0.009) than patients with an ALBI grade I. After a median follow-up of 76 months, 74 (44%) patients experienced recurrence, and 72 (42.9%) patients died. Multivariate analysis revealed that alpha-fetoprotein (AFP) > 200 ng/mL (p = 0.021), number of tumors (p = 0.001), and tumor stage (p = 0.007) were independent prognostic factors for DFS. Additionally, AFP > 200 ng/mL (p = 0.002), ALBI grade II/III (p = 0.002), and tumor stage (p < 0.001) were independent risk factors for poor OS.The preoperative ALBI grade can be used to predict mortality in patients with NBNC-HCC after primary curative resection." @default.
• W3155231617 created "2021-04-26" @default.
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• W3155231617 date "2021-10-19" @default.
• W3155231617 modified "2023-10-14" @default.
• W3155231617 title "Preoperative ALBI grade predicts the outcomes in non-B non-C HCC patients undergoing primary curative resection" @default.
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• W3155231617 doi "https://doi.org/10.1186/s12876-021-01944-w" @default.
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