Matches in SemOpenAlex for { <https://semopenalex.org/work/W3155682457> ?p ?o ?g. }
- W3155682457 abstract "Endotoxemia is characterized by initial uncontrollable inflammation, terminal immune paralysis, significant cell apoptosis and tissue injury, which can aggravate or induce multiple diseases and become one of the complications of many diseases. Therefore, anti-inflammatory and anti-apoptotic therapy is a valuable strategy for the treatment of endotoxemia-induced tissue injury. Traditional Chinese medicine exhibits great advantages in the treatment of endotoxemia. In this review, we have analyzed and summarized the active ingredients and their metabolites of Sanhuang Xiexin Decoction, a famous formula in endotoxemia therapy. We then have summarized the mechanisms of Sanhuang Xiexin Decoction against endotoxemia and its mediated tissue injury. Furthermore, silico strategy was used to evaluate the anti-apoptotic mechanism of anisodamine, a well-known natural product that widely used to improve survival in patients with septic shock. Finally, we also have summarized other anti-apoptotic natural products as well as their therapeutic effects on endotoxemia and its mediated tissue injury." @default.
- W3155682457 created "2021-04-26" @default.
- W3155682457 creator A5024519095 @default.
- W3155682457 creator A5035952199 @default.
- W3155682457 creator A5044513733 @default.
- W3155682457 creator A5046529198 @default.
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- W3155682457 creator A5063003755 @default.
- W3155682457 creator A5065836184 @default.
- W3155682457 creator A5078085004 @default.
- W3155682457 creator A5084948313 @default.
- W3155682457 date "2021-04-21" @default.
- W3155682457 modified "2023-09-27" @default.
- W3155682457 title "Anti-Apoptotic Role of Sanhuang Xiexin Decoction and Anisodamine in Endotoxemia" @default.
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