FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3155762233> ?p ?o ?g. }

• W3155762233 abstract "Abstract Synaptic tagging and capture (STC) is a molecular mechanism that accounts for the consolidation of synaptic changes induced by plasticity. To link this mechanism to long-term memory and thereby to the level of behavior, its dynamics on the level of recurrent networks have to be understood. To this end, we employ a biologically detailed neural network model of spiking neurons featuring STC, which models the learning and consolidation of long-term memory representations. Using this model, we investigate the effects of different organizational paradigms of multiple memory representations, and demonstrate a proof of principle for priming on long timescales. We examine these effects considering the spontaneous activation of memory representations as the network is driven by background noise. Our first finding is that the order in which the memory representations are learned significantly biases the likelihood of spontaneous activation towards more recently learned memory representations. Secondly, we find that hub-like structures counter this learning order effect for representations with less overlaps. We show that long-term depression is the mechanism underlying these findings, and that intermediate consolidation in between learning the individual representations strongly alters the described effects. Finally, we employ STC to demonstrate the priming of a long-term memory representation on a timescale of minutes to hours. As shown by these findings, our model provides a mechanistic synaptic and neuronal basis for known behavioral effects." @default.
• W3155762233 created "2021-04-26" @default.
• W3155762233 creator A5051573698 @default.
• W3155762233 creator A5084861593 @default.
• W3155762233 date "2021-04-16" @default.
• W3155762233 modified "2023-09-23" @default.
• W3155762233 title "Organization and priming of long-term memory representations with two-phase plasticity" @default.
• W3155762233 cites W1582051163 @default.
• W3155762233 cites W1603661052 @default.
• W3155762233 cites W1884265787 @default.
• W3155762233 cites W1967019061 @default.
• W3155762233 cites W1968906215 @default.
• W3155762233 cites W1969507049 @default.
• W3155762233 cites W1972970790 @default.
• W3155762233 cites W1981620514 @default.
• W3155762233 cites W1987873266 @default.
• W3155762233 cites W1996874802 @default.
• W3155762233 cites W2001788447 @default.
• W3155762233 cites W2008675881 @default.
• W3155762233 cites W2011882079 @default.
• W3155762233 cites W2014295524 @default.
• W3155762233 cites W2017547127 @default.
• W3155762233 cites W2022760627 @default.
• W3155762233 cites W2023913445 @default.
• W3155762233 cites W2025687881 @default.
• W3155762233 cites W2025953124 @default.
• W3155762233 cites W2027850049 @default.
• W3155762233 cites W2030281528 @default.
• W3155762233 cites W2035461931 @default.
• W3155762233 cites W2035527322 @default.
• W3155762233 cites W2043487837 @default.
• W3155762233 cites W2046455598 @default.
• W3155762233 cites W2049324847 @default.
• W3155762233 cites W2049511526 @default.
• W3155762233 cites W2051716212 @default.
• W3155762233 cites W2056179104 @default.
• W3155762233 cites W2060322330 @default.
• W3155762233 cites W2060542399 @default.
• W3155762233 cites W2064913240 @default.
• W3155762233 cites W2068334571 @default.
• W3155762233 cites W2069469260 @default.
• W3155762233 cites W2071852876 @default.
• W3155762233 cites W2079197655 @default.
• W3155762233 cites W2081265980 @default.
• W3155762233 cites W2087764343 @default.
• W3155762233 cites W2093277776 @default.
• W3155762233 cites W2098010889 @default.
• W3155762233 cites W2107165322 @default.
• W3155762233 cites W2108525416 @default.
• W3155762233 cites W2109740547 @default.
• W3155762233 cites W2113345172 @default.
• W3155762233 cites W2115751451 @default.
• W3155762233 cites W2146883276 @default.
• W3155762233 cites W2148389554 @default.
• W3155762233 cites W2153561332 @default.
• W3155762233 cites W2155253745 @default.
• W3155762233 cites W2157092518 @default.
• W3155762233 cites W2160691458 @default.
• W3155762233 cites W2161432648 @default.
• W3155762233 cites W2168462263 @default.
• W3155762233 cites W2203645894 @default.
• W3155762233 cites W2241046857 @default.
• W3155762233 cites W2342539172 @default.
• W3155762233 cites W2396075472 @default.
• W3155762233 cites W2404947714 @default.
• W3155762233 cites W2487523824 @default.
• W3155762233 cites W2488937931 @default.
• W3155762233 cites W2516483676 @default.
• W3155762233 cites W2583072564 @default.
• W3155762233 cites W2604617013 @default.
• W3155762233 cites W2743518561 @default.
• W3155762233 cites W2806744336 @default.
• W3155762233 cites W2808647362 @default.
• W3155762233 cites W2900696043 @default.
• W3155762233 cites W2963551839 @default.
• W3155762233 cites W3034847197 @default.
• W3155762233 cites W3133994644 @default.
• W3155762233 cites W4211044912 @default.
• W3155762233 cites W4233900285 @default.
• W3155762233 cites W4238614602 @default.
• W3155762233 cites W4245942056 @default.
• W3155762233 cites W4248079557 @default.
• W3155762233 cites W4251602308 @default.
• W3155762233 cites W4256074087 @default.
• W3155762233 doi "https://doi.org/10.1101/2021.04.15.439982" @default.
• W3155762233 hasPublicationYear "2021" @default.
• W3155762233 type Work @default.
• W3155762233 sameAs 3155762233 @default.
• W3155762233 citedByCount "0" @default.
• W3155762233 crossrefType "posted-content" @default.
• W3155762233 hasAuthorship W3155762233A5051573698 @default.
• W3155762233 hasAuthorship W3155762233A5084861593 @default.
• W3155762233 hasBestOaLocation W31557622331 @default.
• W3155762233 hasConcept C100701293 @default.
• W3155762233 hasConcept C11731999 @default.
• W3155762233 hasConcept C121332964 @default.
• W3155762233 hasConcept C154945302 @default.
• W3155762233 hasConcept C15744967 @default.
• W3155762233 hasConcept C169760540 @default.
• W3155762233 hasConcept C170493617 @default.

• next