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- W3155780402 abstract "Serratia marcescens is a prolific producer of the red, membrane-associated pigment prodigiosin. Earlier work has established both a positive role for prodigiosin in ATP production during the population lag phase and a negative role during high-rate, low cell density growth. This study uses the growth rate and growth phase modulation afforded by chemostat culture to extend prodigiosin functional analysis to the high-density and stationary phases. Cellular levels of prodigiosin were positively associated with cellular levels of ATP during high-density growth, and artificial pigment induction during this phase increased cellular ATP levels. Following peak high-density ATP per cell, the early stationary phase enabled significant population growth, while prodigiosin levels remained high and ATP declined. During the late stationary phase, ATP per cell was positively associated with prodigiosin per cell, while both declined during continued growth. These results provide correlational evidence for the multiple effects of prodigiosin pigment on ATP production throughout the growth cycle. Earlier work and the data presented here enable the formulation of a working model for the oscillating relationships between cellular levels of ATP and prodigiosin during batch culture." @default.
- W3155780402 created "2021-04-26" @default.
- W3155780402 creator A5058473229 @default.
- W3155780402 date "2021-09-01" @default.
- W3155780402 modified "2023-10-18" @default.
- W3155780402 title "Associations between cellular levels of ATP and prodigiosin pigment throughout the growth cycle of <i>Serratia marcescens</i>" @default.
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- W3155780402 doi "https://doi.org/10.1139/cjm-2020-0619" @default.
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