Matches in SemOpenAlex for { <https://semopenalex.org/work/W3155855963> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W3155855963 abstract "To describe retinal findings in a patient with mucopolysaccharidosis type I (MPS I) that underwent an early treatment with hematopoietic stem cell transplantation (HSCT) and enzyme replacement therapy (ERT). Case Report. We describe a case of a 12-year-old female with a biochemical and genetic diagnosis of MPS I. She underwent HSCT and ERT on the first year of life. The visual acuity was 5/10 in both eyes and she had bilateral grade 2 corneal haze. Spectral domain optical coherence tomography (SD-OCT) revealed thickening of the external limiting membrane (ELM) at the fovea. In the parafoveal and perifoveal regions, SD-OCT displayed a loss of the interdigitation, ellipsoid, and myoid zones and of the ELM accompanied by progressive thinning of the outer nuclear layer. Fundus infrared imaging revealed a hyperreflective ring centred on the fovea and hyporeflective areas in temporal parafoveal regions in both eyes. En face OCT imaging revealed two hyperreflective rings on the outer retinal level.This patient developed macular changes with foveal deposition of hyperreflective material and parafoveal thinning, despite early systemic treatment. Systemic therapies can provide an increase in life expectancy and stabilize visual acuity and corneal clouding, although their effect on retinal degeneration is unknown." @default.
- W3155855963 created "2021-04-26" @default.
- W3155855963 creator A5005234046 @default.
- W3155855963 creator A5023369989 @default.
- W3155855963 creator A5034767846 @default.
- W3155855963 creator A5039670363 @default.
- W3155855963 creator A5056488605 @default.
- W3155855963 creator A5066480126 @default.
- W3155855963 creator A5071296307 @default.
- W3155855963 creator A5075846439 @default.
- W3155855963 creator A5079262007 @default.
- W3155855963 date "2021-04-12" @default.
- W3155855963 modified "2023-09-23" @default.
- W3155855963 title "Macular Changes in a Mucopolysaccharidosis Type I Patient with Earlier Systemic Therapies" @default.
- W3155855963 cites W1418744509 @default.
- W3155855963 cites W1969828870 @default.
- W3155855963 cites W1985211153 @default.
- W3155855963 cites W1985801121 @default.
- W3155855963 cites W2005797168 @default.
- W3155855963 cites W2057594413 @default.
- W3155855963 cites W2085932314 @default.
- W3155855963 cites W2098800226 @default.
- W3155855963 cites W2120277028 @default.
- W3155855963 cites W2144481978 @default.
- W3155855963 cites W2145253443 @default.
- W3155855963 cites W2419408934 @default.
- W3155855963 cites W2532643135 @default.
- W3155855963 cites W2761097164 @default.
- W3155855963 cites W4254168211 @default.
- W3155855963 doi "https://doi.org/10.1155/2021/8866837" @default.
- W3155855963 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8267582" @default.
- W3155855963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34306784" @default.
- W3155855963 hasPublicationYear "2021" @default.
- W3155855963 type Work @default.
- W3155855963 sameAs 3155855963 @default.
- W3155855963 citedByCount "1" @default.
- W3155855963 countsByYear W31558559632023 @default.
- W3155855963 crossrefType "journal-article" @default.
- W3155855963 hasAuthorship W3155855963A5005234046 @default.
- W3155855963 hasAuthorship W3155855963A5023369989 @default.
- W3155855963 hasAuthorship W3155855963A5034767846 @default.
- W3155855963 hasAuthorship W3155855963A5039670363 @default.
- W3155855963 hasAuthorship W3155855963A5056488605 @default.
- W3155855963 hasAuthorship W3155855963A5066480126 @default.
- W3155855963 hasAuthorship W3155855963A5071296307 @default.
- W3155855963 hasAuthorship W3155855963A5075846439 @default.
- W3155855963 hasAuthorship W3155855963A5079262007 @default.
- W3155855963 hasBestOaLocation W31558559631 @default.
- W3155855963 hasConcept C118487528 @default.
- W3155855963 hasConcept C142724271 @default.
- W3155855963 hasConcept C2776391266 @default.
- W3155855963 hasConcept C2778024200 @default.
- W3155855963 hasConcept C2778231335 @default.
- W3155855963 hasConcept C2778257484 @default.
- W3155855963 hasConcept C2778818243 @default.
- W3155855963 hasConcept C2779416428 @default.
- W3155855963 hasConcept C2780098626 @default.
- W3155855963 hasConcept C2780827179 @default.
- W3155855963 hasConcept C2781040256 @default.
- W3155855963 hasConcept C71924100 @default.
- W3155855963 hasConceptScore W3155855963C118487528 @default.
- W3155855963 hasConceptScore W3155855963C142724271 @default.
- W3155855963 hasConceptScore W3155855963C2776391266 @default.
- W3155855963 hasConceptScore W3155855963C2778024200 @default.
- W3155855963 hasConceptScore W3155855963C2778231335 @default.
- W3155855963 hasConceptScore W3155855963C2778257484 @default.
- W3155855963 hasConceptScore W3155855963C2778818243 @default.
- W3155855963 hasConceptScore W3155855963C2779416428 @default.
- W3155855963 hasConceptScore W3155855963C2780098626 @default.
- W3155855963 hasConceptScore W3155855963C2780827179 @default.
- W3155855963 hasConceptScore W3155855963C2781040256 @default.
- W3155855963 hasConceptScore W3155855963C71924100 @default.
- W3155855963 hasLocation W31558559631 @default.
- W3155855963 hasLocation W31558559632 @default.
- W3155855963 hasLocation W31558559633 @default.
- W3155855963 hasOpenAccess W3155855963 @default.
- W3155855963 hasPrimaryLocation W31558559631 @default.
- W3155855963 hasRelatedWork W10596190 @default.
- W3155855963 hasRelatedWork W10941023 @default.
- W3155855963 hasRelatedWork W11789985 @default.
- W3155855963 hasRelatedWork W15947869 @default.
- W3155855963 hasRelatedWork W3018269 @default.
- W3155855963 hasRelatedWork W3909081 @default.
- W3155855963 hasRelatedWork W6270809 @default.
- W3155855963 hasRelatedWork W7981970 @default.
- W3155855963 hasRelatedWork W12832372 @default.
- W3155855963 hasRelatedWork W19677302 @default.
- W3155855963 isParatext "false" @default.
- W3155855963 isRetracted "false" @default.
- W3155855963 magId "3155855963" @default.
- W3155855963 workType "article" @default.