FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3155942867> ?p ?o ?g. }

• W3155942867 abstract "To the Editor: We read with great interest the article published by Taylor et al1 entitled “Outcomes and Spectrum of Major Neurovascular Events Among COVID-19 Patients: A 3-Center Experience,” where the authors describe the clinical course and results of a series of cases of patients with COVID-19, who developed cerebrovascular events. We thank the authors1 for providing this type of evidence, which is considered valuable; however, we would like to make some observations. Patients affected by COVID-19 may have multiple neurological manifestations in addition to cerebrovascular involvement. In a systematic review, the following neurological disorders were found in descending order of prevalence: headache (16.8%), dizziness (13.9%), altered state of consciousness (11.2%), vomiting (6.3%), epileptic seizures (1.7%), neuralgia (1.2%), and ataxia (0.7%), being the stroke, the presumptive diagnosis in the third place of consideration, below the acute viral meningoencephalitis and the hypoxic encephalopathy, evidencing then that the suspicion of stroke becomes difficult.2 Additionally, Chen et al3 reported that anosmia and dysgeusia (nonspecific symptoms) are the most common neurological symptoms in patients with COVID-19, so the approach for these individuals based on their risk factors to decrease the likelihood of developing complications such as stroke is complex.3 They also found that acute cerebrovascular episodes occurred mainly in patients with advanced age, severe progression of COVID-19 disease, cardiovascular risk factors (hypertension, diabetes), and history of cardiovascular disease.3 Advanced age remains one of the main risk factors for the development of severe cerebrovascular events in this type of patients. Goldberg et al4 reported a case of COVID-19 with acute cerebral infarction, due to the instability of a proximal stenosis of the internal carotid artery at the bifurcation level, and decreased distal flow in the right medial cerebral artery and in both anterior cerebral arteries.4 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been described as a neurotropic virus, from which numerous mechanisms of injury to nervous tissue have been postulated, such as, through the infection of the olfactory epithelium, infection of peripheral nerve endings with structural spread, vascular diffusion, and lesion secondary to immune response, among others, which could ultimately cause serious complications of the disease such as infectious toxic encephalopathy, acute viral meningoencephalitis, and severe cerebrovascular disease.5 Finally, endothelial damage is an extremely important element in the pathogenesis of stroke in patients with COVID-19, because, at the local level, SARS-CoV-2 infects cells by binding the virus's Spike protein to the angiotensin-converting enzyme receptor 2 (ACE2) expressed in the capillary endothelium. Expression of this receptor was recently found in other superspecialized tissues such as glial cells,6 cerebral cortex, black substance, brain stem, posterior area of the hypothalamus, and striated body.7 In this order of ideas, not only patients who express the phenotype of COVID-19 may have a risk of thrombogenesis and cerebral ischemia due to the instability of previous pathological conditions, but the state of biochemical hypercoagulability that generates direct vascular injury is sufficient to compromise a person's life or functional capacity. Funding This study did not receive any funding or financial support. Disclosures The authors have no personal, financial, or institutional interest in any of the drugs, materials, or devices described in this article." @default.
• W3155942867 created "2021-04-26" @default.
• W3155942867 creator A5006106538 @default.
• W3155942867 creator A5013775596 @default.
• W3155942867 creator A5045432567 @default.
• W3155942867 creator A5064623732 @default.
• W3155942867 creator A5072074601 @default.
• W3155942867 date "2021-04-21" @default.
• W3155942867 modified "2023-10-15" @default.
• W3155942867 title "Letter: Outcomes and Spectrum of Major Neurovascular Events Among COVID-19 Patients: A 3-Center Experience" @default.
• W3155942867 cites W3013270768 @default.
• W3155942867 cites W3024888449 @default.
• W3155942867 cites W3030230389 @default.
• W3155942867 cites W3043216367 @default.
• W3155942867 cites W4206809647 @default.
• W3155942867 doi "https://doi.org/10.1093/neuopn/okab007" @default.
• W3155942867 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8083208" @default.
• W3155942867 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34632393" @default.
• W3155942867 hasPublicationYear "2021" @default.
• W3155942867 type Work @default.
• W3155942867 sameAs 3155942867 @default.
• W3155942867 citedByCount "1" @default.
• W3155942867 countsByYear W31559428672021 @default.
• W3155942867 crossrefType "journal-article" @default.
• W3155942867 hasAuthorship W3155942867A5006106538 @default.
• W3155942867 hasAuthorship W3155942867A5013775596 @default.
• W3155942867 hasAuthorship W3155942867A5045432567 @default.
• W3155942867 hasAuthorship W3155942867A5064623732 @default.
• W3155942867 hasAuthorship W3155942867A5072074601 @default.
• W3155942867 hasBestOaLocation W31559428671 @default.
• W3155942867 hasConcept C126322002 @default.
• W3155942867 hasConcept C127413603 @default.
• W3155942867 hasConcept C177713679 @default.
• W3155942867 hasConcept C187212893 @default.
• W3155942867 hasConcept C197934379 @default.
• W3155942867 hasConcept C2777054765 @default.
• W3155942867 hasConcept C2779134260 @default.
• W3155942867 hasConcept C2780645631 @default.
• W3155942867 hasConcept C71924100 @default.
• W3155942867 hasConcept C78519656 @default.
• W3155942867 hasConceptScore W3155942867C126322002 @default.
• W3155942867 hasConceptScore W3155942867C127413603 @default.
• W3155942867 hasConceptScore W3155942867C177713679 @default.
• W3155942867 hasConceptScore W3155942867C187212893 @default.
• W3155942867 hasConceptScore W3155942867C197934379 @default.
• W3155942867 hasConceptScore W3155942867C2777054765 @default.
• W3155942867 hasConceptScore W3155942867C2779134260 @default.
• W3155942867 hasConceptScore W3155942867C2780645631 @default.
• W3155942867 hasConceptScore W3155942867C71924100 @default.
• W3155942867 hasConceptScore W3155942867C78519656 @default.
• W3155942867 hasIssue "2" @default.
• W3155942867 hasLocation W31559428671 @default.
• W3155942867 hasLocation W31559428672 @default.
• W3155942867 hasLocation W31559428673 @default.
• W3155942867 hasOpenAccess W3155942867 @default.
• W3155942867 hasPrimaryLocation W31559428671 @default.
• W3155942867 hasRelatedWork W1839838842 @default.
• W3155942867 hasRelatedWork W1980950179 @default.
• W3155942867 hasRelatedWork W2076985335 @default.
• W3155942867 hasRelatedWork W2081275162 @default.
• W3155942867 hasRelatedWork W2090704721 @default.
• W3155942867 hasRelatedWork W2124125394 @default.
• W3155942867 hasRelatedWork W2266469091 @default.
• W3155942867 hasRelatedWork W2991533465 @default.
• W3155942867 hasRelatedWork W3145039868 @default.
• W3155942867 hasRelatedWork W4229748659 @default.
• W3155942867 hasVolume "2" @default.
• W3155942867 isParatext "false" @default.
• W3155942867 isRetracted "false" @default.
• W3155942867 magId "3155942867" @default.
• W3155942867 workType "letter" @default.