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- W3156132912 startingPage "336" @default.
- W3156132912 abstract "Obesity caused by the overconsumption of calories has increased to epidemic proportions. Insulin resistance is often associated with an increased adiposity and is a precipitating factor in the development of cardiovascular disease, type 2 diabetes, and altered metabolic health. Of the various factors contributing to metabolic impairments, nutrition is the major modifiable factor that can be targeted to counter the rising prevalence of obesity and metabolic diseases. However, the macronutrient composition of a nutritionally balanced “healthy diet” are unclear, and so far, no tested dietary intervention has been successful in achieving long-term compliance and reductions in body weight and associated beneficial health outcomes. In the current review, we briefly describe the role of the three major macronutrients, carbohydrates, fats, and proteins, and their role in metabolic health, and provide mechanistic insights. We also discuss how an integrated multi-dimensional approach to nutritional science could help in reconciling apparently conflicting findings." @default.
- W3156132912 created "2021-04-26" @default.
- W3156132912 creator A5024147668 @default.
- W3156132912 creator A5039344268 @default.
- W3156132912 creator A5062326737 @default.
- W3156132912 creator A5074667950 @default.
- W3156132912 date "2021-04-16" @default.
- W3156132912 modified "2023-09-26" @default.
- W3156132912 title "Macronutrient Determinants of Obesity, Insulin Resistance and Metabolic Health" @default.
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