Matches in SemOpenAlex for { <https://semopenalex.org/work/W3156304196> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3156304196 abstract "Abstract In biological networks, steady state dynamics of cell-fate regulatory genes often exhibit Mushroom and Isola kind of bifurcations. How these complex bifurcations emerge for these complex networks, and what are the minimal network structures that can generate these bifurcations, remain elusive. Herein, by employing Waddington’s landscape theory and bifurcation analysis, we have shown that both Mushroom and Isola bifurcations can be realized with four minimal network motifs that are constituted by combining positive feedback motifs with different types of incoherent feedback motifs. Our study demonstrates that the intrinsic bi-stable dynamics due to the presence of the positive feedback motif can be fine-tuned by altering the extent of the incoherence of these proposed minimal networks to orchestrate these complex bifurcations. These modeling insights will be useful in identifying and analyzing possible network motifs that may give rise to either Mushroom or Isola bifurcation in other biological systems." @default.
- W3156304196 created "2021-04-26" @default.
- W3156304196 creator A5003801964 @default.
- W3156304196 creator A5071065804 @default.
- W3156304196 date "2021-04-22" @default.
- W3156304196 modified "2023-09-23" @default.
- W3156304196 title "Incoherent modulation of bi-stable dynamics orchestrates the Mushroom and Isola bifurcations" @default.
- W3156304196 cites W1943734593 @default.
- W3156304196 cites W1978486653 @default.
- W3156304196 cites W1980561748 @default.
- W3156304196 cites W2057680921 @default.
- W3156304196 cites W2061425021 @default.
- W3156304196 cites W2063854986 @default.
- W3156304196 cites W2072319015 @default.
- W3156304196 cites W2106362845 @default.
- W3156304196 cites W2119571991 @default.
- W3156304196 cites W2123973944 @default.
- W3156304196 cites W2145444336 @default.
- W3156304196 cites W2152407435 @default.
- W3156304196 cites W2168026765 @default.
- W3156304196 cites W2361838659 @default.
- W3156304196 cites W2782684024 @default.
- W3156304196 cites W2788686648 @default.
- W3156304196 cites W2901542704 @default.
- W3156304196 cites W2950926073 @default.
- W3156304196 cites W2973361953 @default.
- W3156304196 cites W3097717962 @default.
- W3156304196 cites W3128514013 @default.
- W3156304196 cites W4238889518 @default.
- W3156304196 doi "https://doi.org/10.1101/2021.04.22.440901" @default.
- W3156304196 hasPublicationYear "2021" @default.
- W3156304196 type Work @default.
- W3156304196 sameAs 3156304196 @default.
- W3156304196 citedByCount "1" @default.
- W3156304196 countsByYear W31563041962022 @default.
- W3156304196 crossrefType "posted-content" @default.
- W3156304196 hasAuthorship W3156304196A5003801964 @default.
- W3156304196 hasAuthorship W3156304196A5071065804 @default.
- W3156304196 hasBestOaLocation W31563041961 @default.
- W3156304196 hasConcept C114614502 @default.
- W3156304196 hasConcept C121332964 @default.
- W3156304196 hasConcept C121864883 @default.
- W3156304196 hasConcept C126701199 @default.
- W3156304196 hasConcept C134306372 @default.
- W3156304196 hasConcept C145912823 @default.
- W3156304196 hasConcept C154945302 @default.
- W3156304196 hasConcept C158622935 @default.
- W3156304196 hasConcept C165801399 @default.
- W3156304196 hasConcept C172435161 @default.
- W3156304196 hasConcept C186060115 @default.
- W3156304196 hasConcept C24890656 @default.
- W3156304196 hasConcept C2775924081 @default.
- W3156304196 hasConcept C2781349735 @default.
- W3156304196 hasConcept C28225019 @default.
- W3156304196 hasConcept C33923547 @default.
- W3156304196 hasConcept C34947359 @default.
- W3156304196 hasConcept C41008148 @default.
- W3156304196 hasConcept C47446073 @default.
- W3156304196 hasConcept C62520636 @default.
- W3156304196 hasConcept C86803240 @default.
- W3156304196 hasConcept C93586867 @default.
- W3156304196 hasConceptScore W3156304196C114614502 @default.
- W3156304196 hasConceptScore W3156304196C121332964 @default.
- W3156304196 hasConceptScore W3156304196C121864883 @default.
- W3156304196 hasConceptScore W3156304196C126701199 @default.
- W3156304196 hasConceptScore W3156304196C134306372 @default.
- W3156304196 hasConceptScore W3156304196C145912823 @default.
- W3156304196 hasConceptScore W3156304196C154945302 @default.
- W3156304196 hasConceptScore W3156304196C158622935 @default.
- W3156304196 hasConceptScore W3156304196C165801399 @default.
- W3156304196 hasConceptScore W3156304196C172435161 @default.
- W3156304196 hasConceptScore W3156304196C186060115 @default.
- W3156304196 hasConceptScore W3156304196C24890656 @default.
- W3156304196 hasConceptScore W3156304196C2775924081 @default.
- W3156304196 hasConceptScore W3156304196C2781349735 @default.
- W3156304196 hasConceptScore W3156304196C28225019 @default.
- W3156304196 hasConceptScore W3156304196C33923547 @default.
- W3156304196 hasConceptScore W3156304196C34947359 @default.
- W3156304196 hasConceptScore W3156304196C41008148 @default.
- W3156304196 hasConceptScore W3156304196C47446073 @default.
- W3156304196 hasConceptScore W3156304196C62520636 @default.
- W3156304196 hasConceptScore W3156304196C86803240 @default.
- W3156304196 hasConceptScore W3156304196C93586867 @default.
- W3156304196 hasLocation W31563041961 @default.
- W3156304196 hasOpenAccess W3156304196 @default.
- W3156304196 hasPrimaryLocation W31563041961 @default.
- W3156304196 hasRelatedWork W1997779361 @default.
- W3156304196 hasRelatedWork W2003903477 @default.
- W3156304196 hasRelatedWork W2067892548 @default.
- W3156304196 hasRelatedWork W223567488 @default.
- W3156304196 hasRelatedWork W2352647455 @default.
- W3156304196 hasRelatedWork W2411025585 @default.
- W3156304196 hasRelatedWork W2773117060 @default.
- W3156304196 hasRelatedWork W3156304196 @default.
- W3156304196 hasRelatedWork W3195105109 @default.
- W3156304196 hasRelatedWork W3207323133 @default.
- W3156304196 isParatext "false" @default.
- W3156304196 isRetracted "false" @default.
- W3156304196 magId "3156304196" @default.
- W3156304196 workType "article" @default.