Matches in SemOpenAlex for { <https://semopenalex.org/work/W3156459080> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W3156459080 abstract "The present study aimed to elucidate the clinical values of miR-337-3p, miR-484, miR-582, and miR-3677 in patients with osteosarcoma.After extracting RNA from serum samples of healthy volunteers, OS patients, and periostitis patients, the real-time quantitative polymerase chain reaction (RT-qPCR) analysis was carried out. Afterwards, the receiver operating characteristic (ROC) assays were conducted in order to identify the area under the curves of certain microRNAs in OS. Finally, the log-rank survival analysis was used to analyze the five-year survival rate and disease-free survival rate of OS patients with aberrant microRNA expressions.From the results, miR-337-3p, miR-484, miR-582, and miR-3677 were remarkably decreased in OS cell lines, tumor tissues, and serum samples of OS patients. Furthermore, receiver operating characteristic (ROC) analysis verified that serum miR-337-3p, miR-484, miR-582, miR-711 and miR-3677 had favorable diagnostic values for identifying OS from periostitis patients with the area under the curves of 0.9434, 0.8760, 0.717,0 and 0.8705 and from healthy volunteers with the area under the curves 0.8218, 0.8358, 0.8008, and 0.7141, respectively. After surgery, serum miR-337-3p, miR-484, miR-582, and miR-3677 were dramatically increased. Meanwhile, lower expressions of miR-337-3p, miR-484, miR-582 and miR-3677 were strongly correlated with clinical stage and metastasis. Last but not the least, the log-rank survival analysis demonstrated that lower expressions of miR-337-3p, miR-484, miR-582, and miR-3677 were related to unfavorable prognosis in OS patients.Our study verified and illustrated the clinical values of miR-337-3p, miR-484, miR-582, and miR-3677 for the detection and prognosis of OS." @default.
- W3156459080 created "2021-04-26" @default.
- W3156459080 creator A5066275647 @default.
- W3156459080 creator A5087185685 @default.
- W3156459080 date "2021-01-01" @default.
- W3156459080 modified "2023-09-26" @default.
- W3156459080 title "Identification of Serum miR-337-3p, miR-484, miR-582, and miR-3677 as Promising Biomarkers for Osteosarcoma" @default.
- W3156459080 doi "https://doi.org/10.7754/clin.lab.2020.200455" @default.
- W3156459080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33865271" @default.
- W3156459080 hasPublicationYear "2021" @default.
- W3156459080 type Work @default.
- W3156459080 sameAs 3156459080 @default.
- W3156459080 citedByCount "4" @default.
- W3156459080 countsByYear W31564590802022 @default.
- W3156459080 countsByYear W31564590802023 @default.
- W3156459080 crossrefType "journal-article" @default.
- W3156459080 hasAuthorship W3156459080A5066275647 @default.
- W3156459080 hasAuthorship W3156459080A5087185685 @default.
- W3156459080 hasConcept C104317684 @default.
- W3156459080 hasConcept C126322002 @default.
- W3156459080 hasConcept C145059251 @default.
- W3156459080 hasConcept C2777760704 @default.
- W3156459080 hasConcept C502942594 @default.
- W3156459080 hasConcept C55493867 @default.
- W3156459080 hasConcept C58471807 @default.
- W3156459080 hasConcept C71924100 @default.
- W3156459080 hasConcept C86803240 @default.
- W3156459080 hasConceptScore W3156459080C104317684 @default.
- W3156459080 hasConceptScore W3156459080C126322002 @default.
- W3156459080 hasConceptScore W3156459080C145059251 @default.
- W3156459080 hasConceptScore W3156459080C2777760704 @default.
- W3156459080 hasConceptScore W3156459080C502942594 @default.
- W3156459080 hasConceptScore W3156459080C55493867 @default.
- W3156459080 hasConceptScore W3156459080C58471807 @default.
- W3156459080 hasConceptScore W3156459080C71924100 @default.
- W3156459080 hasConceptScore W3156459080C86803240 @default.
- W3156459080 hasIssue "04/2021" @default.
- W3156459080 hasLocation W31564590801 @default.
- W3156459080 hasLocation W31564590802 @default.
- W3156459080 hasOpenAccess W3156459080 @default.
- W3156459080 hasPrimaryLocation W31564590801 @default.
- W3156459080 hasRelatedWork W1553867384 @default.
- W3156459080 hasRelatedWork W1988628426 @default.
- W3156459080 hasRelatedWork W2560236165 @default.
- W3156459080 hasRelatedWork W2781680339 @default.
- W3156459080 hasRelatedWork W2901643934 @default.
- W3156459080 hasRelatedWork W2912679909 @default.
- W3156459080 hasRelatedWork W2955113018 @default.
- W3156459080 hasRelatedWork W3039576629 @default.
- W3156459080 hasRelatedWork W625166377 @default.
- W3156459080 hasRelatedWork W4206851580 @default.
- W3156459080 hasVolume "67" @default.
- W3156459080 isParatext "false" @default.
- W3156459080 isRetracted "false" @default.
- W3156459080 magId "3156459080" @default.
- W3156459080 workType "article" @default.