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- W315652939 abstract "SUMMARY: Labelling of guinea-pig brain in vivo with 32 P 1 . produced nerve-endings in which phosphatidic acid and phosphatidylinositol were the major labelled lipids. Labelled phosphatidylinositol was associated with synaptic vesicles and labelled phosphatidate with a microsomal fraction containing some plasma membrane and endoplasmic reticulum fragments and rich in diacylglycerol kinase. Electrical stimulation in vitro of the synaptosomes caused loss of these labelled lipids from the two fractions described. Entry of external calcium was not required for the lipid effects, nor could calcium ionophore replace electrical stimulation in producing them. Calcium entry into synaptosomes caused loss of labelled triphosphoinositide and the effect was obtained with very small increase in the calcium concentration of the cytoplasm." @default.
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- W315652939 date "1978-01-01" @default.
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- W315652939 title "PHOSPHATIDYLINOSITOL, TRIPHOSPHOINOSITIDE AND SYNAPTIC TRANSMISSION" @default.
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