FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3157133449> ?p ?o ?g. }

• W3157133449 endingPage "9" @default.
• W3157133449 startingPage "1" @default.
• W3157133449 abstract "Ulcerative colitis (UC) is an inflammatory bowel disease that is related to the occurrence of colon cancer. This study aimed to investigate the underlying mechanism by which Yu Shi An Chang Fang (YST) treated UC. 2, 4, 6-trinitrobenzene sulfonic acid (TNBS) was used to construct the UC model. The body weight, fecal viscosity, and fecal bleeding of all mice were recorded every day to calculate the DAI value. The pathological changes in colon tissues were observed by hematoxylin-eosin (H&E) staining. The levels of tumor necrosis factor-α (TNF-α), interleukin-1 beta (IL-1β), interleukin-6 (IL-6), and myeloperoxidase (MPO) reflecting inflammation and the levels of malondialdehyde (MDA), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) reflecting oxidative stress in colon tissues were all measured by their assay kits. The mRNA expression of TNF-α, IL-1β, and IL-6 in colon tissues was detected by quantitative reverse transcription-PCR (qRT-PCR). The expression of proteins related to pyroptosis and the colonic mucosal barrier was analyzed by Western blot. As a result, TNBS caused decreases in body weight and colon lengths, triggered serious histological damage, promoted inflammation, oxidative stress, and pyroptosis, and destroyed the colonic mucosal barrier. The above changes caused by TNBS in colitis mice could be partially reversed by YST. In conclusion, YST ameliorates TNBS-induced UC in mice by reducing the inflammatory response and protecting the intestinal mucosal barrier." @default.
• W3157133449 created "2021-05-10" @default.
• W3157133449 creator A5024105690 @default.
• W3157133449 creator A5029312878 @default.
• W3157133449 date "2021-05-04" @default.
• W3157133449 modified "2023-10-14" @default.
• W3157133449 title "Yu Shi An Chang Fang Ameliorates TNBS-Induced Colitis in Mice by Reducing Inflammatory Response and Protecting the Intestinal Mucosal Barrier" @default.
• W3157133449 cites W1917406468 @default.
• W3157133449 cites W1966915484 @default.
• W3157133449 cites W1980059877 @default.
• W3157133449 cites W1995661454 @default.
• W3157133449 cites W1997848360 @default.
• W3157133449 cites W2028641592 @default.
• W3157133449 cites W2055624309 @default.
• W3157133449 cites W2086681622 @default.
• W3157133449 cites W2113582196 @default.
• W3157133449 cites W2131766686 @default.
• W3157133449 cites W2146367607 @default.
• W3157133449 cites W2161789287 @default.
• W3157133449 cites W2339658945 @default.
• W3157133449 cites W2565571909 @default.
• W3157133449 cites W2575058461 @default.
• W3157133449 cites W2591036296 @default.
• W3157133449 cites W2606953529 @default.
• W3157133449 cites W2726956030 @default.
• W3157133449 cites W2766046358 @default.
• W3157133449 cites W2791573099 @default.
• W3157133449 cites W2792509463 @default.
• W3157133449 cites W2792959715 @default.
• W3157133449 cites W2800442210 @default.
• W3157133449 cites W2801140633 @default.
• W3157133449 cites W2807446971 @default.
• W3157133449 cites W2898787183 @default.
• W3157133449 cites W2904159701 @default.
• W3157133449 cites W2905221516 @default.
• W3157133449 cites W2913932274 @default.
• W3157133449 cites W2924306602 @default.
• W3157133449 cites W2972283191 @default.
• W3157133449 cites W2982809154 @default.
• W3157133449 cites W2990528901 @default.
• W3157133449 cites W2998604631 @default.
• W3157133449 cites W3008659397 @default.
• W3157133449 cites W3032161741 @default.
• W3157133449 cites W3033288732 @default.
• W3157133449 cites W3098249613 @default.
• W3157133449 cites W3130494218 @default.
• W3157133449 cites W4211138554 @default.
• W3157133449 cites W4237441880 @default.
• W3157133449 doi "https://doi.org/10.1155/2021/8870901" @default.
• W3157133449 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8112936" @default.
• W3157133449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34055024" @default.
• W3157133449 hasPublicationYear "2021" @default.
• W3157133449 type Work @default.
• W3157133449 sameAs 3157133449 @default.
• W3157133449 citedByCount "2" @default.
• W3157133449 countsByYear W31571334492022 @default.
• W3157133449 crossrefType "journal-article" @default.
• W3157133449 hasAuthorship W3157133449A5024105690 @default.
• W3157133449 hasAuthorship W3157133449A5029312878 @default.
• W3157133449 hasBestOaLocation W31571334491 @default.
• W3157133449 hasConcept C104317684 @default.
• W3157133449 hasConcept C125473707 @default.
• W3157133449 hasConcept C126322002 @default.
• W3157133449 hasConcept C142724271 @default.
• W3157133449 hasConcept C164027704 @default.
• W3157133449 hasConcept C17172800 @default.
• W3157133449 hasConcept C17991360 @default.
• W3157133449 hasConcept C181199279 @default.
• W3157133449 hasConcept C185592680 @default.
• W3157133449 hasConcept C203014093 @default.
• W3157133449 hasConcept C203565725 @default.
• W3157133449 hasConcept C204232928 @default.
• W3157133449 hasConcept C2775838275 @default.
• W3157133449 hasConcept C2775862500 @default.
• W3157133449 hasConcept C2776151105 @default.
• W3157133449 hasConcept C2776415932 @default.
• W3157133449 hasConcept C2776914184 @default.
• W3157133449 hasConcept C2777209026 @default.
• W3157133449 hasConcept C2778260677 @default.
• W3157133449 hasConcept C2778401633 @default.
• W3157133449 hasConcept C2778690821 @default.
• W3157133449 hasConcept C2778760513 @default.
• W3157133449 hasConcept C2779134260 @default.
• W3157133449 hasConcept C2780479503 @default.
• W3157133449 hasConcept C538909803 @default.
• W3157133449 hasConcept C55493867 @default.
• W3157133449 hasConcept C71924100 @default.
• W3157133449 hasConcept C74172505 @default.
• W3157133449 hasConceptScore W3157133449C104317684 @default.
• W3157133449 hasConceptScore W3157133449C125473707 @default.
• W3157133449 hasConceptScore W3157133449C126322002 @default.
• W3157133449 hasConceptScore W3157133449C142724271 @default.
• W3157133449 hasConceptScore W3157133449C164027704 @default.
• W3157133449 hasConceptScore W3157133449C17172800 @default.
• W3157133449 hasConceptScore W3157133449C17991360 @default.
• W3157133449 hasConceptScore W3157133449C181199279 @default.
• W3157133449 hasConceptScore W3157133449C185592680 @default.
• W3157133449 hasConceptScore W3157133449C203014093 @default.

• next