FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3157201184> ?p ?o ?g. }

• W3157201184 endingPage "3312" @default.
• W3157201184 startingPage "3292" @default.
• W3157201184 abstract "Abstract Cortical pyramidal neurons (PNs) containing nonphosphorylated neurofilaments (NNFs) localized with the SMI‐32 monoclonal antibody have been shown to be especially vulnerable to degeneration in Alzheimer's disease (AD). The present investigation is the first to study the expression of SMI‐32+ NNFs in neurons of the basolateral nuclear complex of the amygdala (BNC), which contains cortex‐like PNs and nonpyramidal neurons (NPNs). We observed that PNs in the rat basolateral nucleus (BL), but not in the lateral (LAT) or basomedial (BM) nuclei, have significant levels of SMI‐32‐ir in their somata with antibody diluents that did not contain Triton X‐100, but staining in these cells was greatly attenuated when the antibody diluent contained 0.3% Triton. Using Triton‐containing diluents, we found that all SMI‐32+ neurons in all three of the BNC nuclei were NPNs. Using a dual‐labeling immunoperoxidase technique, we demonstrated that most of these SMI‐32+ NPNs were parvalbumin‐positive (PV+) or somatostatin‐positive NPNs but not vasoactive intestinal peptide‐positive or neuropeptide Y‐positive NPNs. Using a technique that combines retrograde tracing with SMI‐32 immunohistochemistry using intermediate levels of Triton in the diluent, we found that all BNC neurons projecting to the mediodorsal thalamic nucleus (MD) were large NPNs, and most were SMI‐32+. In contrast, BNC neurons projecting to the ventral striatum or cerebral cortex were PNs that expressed low levels of SMI‐32 immunoreactivity (SMI‐32‐ir) in the BL, and no SMI‐32‐ir in the LAT or BM. These data suggest that the main neuronal subpopulations in the BNC that degenerate in AD may be PV+ and MD‐projecting NPNs." @default.
• W3157201184 created "2021-05-10" @default.
• W3157201184 creator A5040223434 @default.
• W3157201184 creator A5064778800 @default.
• W3157201184 date "2021-05-14" @default.
• W3157201184 modified "2023-10-18" @default.
• W3157201184 title "Specific neuronal subpopulations in the rat basolateral amygdala express high levels of nonphosphorylated neurofilaments" @default.
• W3157201184 cites W1525169050 @default.
• W3157201184 cites W1569576869 @default.
• W3157201184 cites W1585501195 @default.
• W3157201184 cites W1912705418 @default.
• W3157201184 cites W1947131268 @default.
• W3157201184 cites W1965534328 @default.
• W3157201184 cites W1967024359 @default.
• W3157201184 cites W1970585150 @default.
• W3157201184 cites W1970807381 @default.
• W3157201184 cites W1972444597 @default.
• W3157201184 cites W1974033921 @default.
• W3157201184 cites W1977502547 @default.
• W3157201184 cites W1981590453 @default.
• W3157201184 cites W1984620843 @default.
• W3157201184 cites W1990469555 @default.
• W3157201184 cites W1990474543 @default.
• W3157201184 cites W1991364088 @default.
• W3157201184 cites W1991445375 @default.
• W3157201184 cites W1992730871 @default.
• W3157201184 cites W1996904648 @default.
• W3157201184 cites W1998899272 @default.
• W3157201184 cites W1999900572 @default.
• W3157201184 cites W2001347137 @default.
• W3157201184 cites W2003058471 @default.
• W3157201184 cites W2003660243 @default.
• W3157201184 cites W2004141483 @default.
• W3157201184 cites W2008543026 @default.
• W3157201184 cites W2008544676 @default.
• W3157201184 cites W2011856338 @default.
• W3157201184 cites W2018244586 @default.
• W3157201184 cites W2019000660 @default.
• W3157201184 cites W2019229928 @default.
• W3157201184 cites W2020374304 @default.
• W3157201184 cites W2021282423 @default.
• W3157201184 cites W2026720425 @default.
• W3157201184 cites W2027376690 @default.
• W3157201184 cites W2027524945 @default.
• W3157201184 cites W2029358918 @default.
• W3157201184 cites W2029468871 @default.
• W3157201184 cites W2029603402 @default.
• W3157201184 cites W2032742540 @default.
• W3157201184 cites W2033211327 @default.
• W3157201184 cites W2042067211 @default.
• W3157201184 cites W2042312455 @default.
• W3157201184 cites W2042479971 @default.
• W3157201184 cites W2043803126 @default.
• W3157201184 cites W2044488637 @default.
• W3157201184 cites W2044686824 @default.
• W3157201184 cites W2047229615 @default.
• W3157201184 cites W2047669202 @default.
• W3157201184 cites W2049691406 @default.
• W3157201184 cites W2050071205 @default.
• W3157201184 cites W2052086914 @default.
• W3157201184 cites W2053303406 @default.
• W3157201184 cites W2054296995 @default.
• W3157201184 cites W2056923358 @default.
• W3157201184 cites W205729032 @default.
• W3157201184 cites W2057465705 @default.
• W3157201184 cites W2057974431 @default.
• W3157201184 cites W2058224978 @default.
• W3157201184 cites W2060012297 @default.
• W3157201184 cites W2060687819 @default.
• W3157201184 cites W2061657320 @default.
• W3157201184 cites W2065193709 @default.
• W3157201184 cites W2070909285 @default.
• W3157201184 cites W2071148852 @default.
• W3157201184 cites W2075256849 @default.
• W3157201184 cites W2075312117 @default.
• W3157201184 cites W2075468464 @default.
• W3157201184 cites W2079102265 @default.
• W3157201184 cites W2081085930 @default.
• W3157201184 cites W2084002557 @default.
• W3157201184 cites W2085752437 @default.
• W3157201184 cites W2086051541 @default.
• W3157201184 cites W2094396177 @default.
• W3157201184 cites W2105895575 @default.
• W3157201184 cites W2110915628 @default.
• W3157201184 cites W2112014490 @default.
• W3157201184 cites W2121863189 @default.
• W3157201184 cites W2123095717 @default.
• W3157201184 cites W2139776528 @default.
• W3157201184 cites W2147324044 @default.
• W3157201184 cites W2151920318 @default.
• W3157201184 cites W2163980830 @default.
• W3157201184 cites W2166413386 @default.
• W3157201184 cites W2167578383 @default.
• W3157201184 cites W2318838494 @default.
• W3157201184 cites W2518397136 @default.
• W3157201184 cites W2534475745 @default.
• W3157201184 cites W2602799162 @default.
• W3157201184 cites W2604210857 @default.

• next