FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3157294174> ?p ?o ?g. }

• W3157294174 abstract "10-Alkylthiocolchicines have been obtained and characterized by spectroscopic methods and their biological activities as: cytotoxic, anti-inflammatory and analgesic activities have been tested. Cytotoxic activity against SKOV-3 ovarian cell line for 10-alkylthiocolchicine analogues was reported and tested compounds showed to be more active than commonly used doxorubicin. Some of tested C-10 alkylthiolated colchicines have been found to exhibit cytotoxicity at levels comparable to that of the natural product-colchicine. 10-Methylthiocolchicine has IC50 = 8 nM and 10-ethylthiocolchicine has IC50 = 47 nM in comparison to colchicine IC50 = 37 nM. Moreover for 10-alkylthioderivatives apoptosis test, cyclin B1 and cell cycle tests were performed. 10-n-Butylthiocolchicine was tested for anti-inflammatory and analgesic activities it showed to produce analgesic rather than anti-inflammatory effect." @default.
• W3157294174 created "2021-05-10" @default.
• W3157294174 creator A5000752192 @default.
• W3157294174 creator A5026961997 @default.
• W3157294174 creator A5045339907 @default.
• W3157294174 creator A5047516625 @default.
• W3157294174 creator A5050110012 @default.
• W3157294174 creator A5065681889 @default.
• W3157294174 creator A5069196659 @default.
• W3157294174 creator A5073810747 @default.
• W3157294174 creator A5081463984 @default.
• W3157294174 creator A5082731567 @default.
• W3157294174 date "2021-04-27" @default.
• W3157294174 modified "2023-10-10" @default.
• W3157294174 title "Cytotoxic, analgesic and anti-inflammatory activity of colchicine and its C-10 sulfur containing derivatives" @default.
• W3157294174 cites W1978604673 @default.
• W3157294174 cites W1981819970 @default.
• W3157294174 cites W1989423171 @default.
• W3157294174 cites W1997453554 @default.
• W3157294174 cites W2014207475 @default.
• W3157294174 cites W2024941456 @default.
• W3157294174 cites W2025269179 @default.
• W3157294174 cites W2027177359 @default.
• W3157294174 cites W2034056966 @default.
• W3157294174 cites W2047733244 @default.
• W3157294174 cites W2053741226 @default.
• W3157294174 cites W2065188361 @default.
• W3157294174 cites W2091886819 @default.
• W3157294174 cites W2113115666 @default.
• W3157294174 cites W2128916778 @default.
• W3157294174 cites W2134049088 @default.
• W3157294174 cites W2137725057 @default.
• W3157294174 cites W2137947355 @default.
• W3157294174 cites W2139972978 @default.
• W3157294174 cites W2149127327 @default.
• W3157294174 cites W2168421647 @default.
• W3157294174 cites W2172081252 @default.
• W3157294174 cites W2332063536 @default.
• W3157294174 cites W2409304886 @default.
• W3157294174 cites W2463306689 @default.
• W3157294174 cites W2523300371 @default.
• W3157294174 cites W2886246210 @default.
• W3157294174 cites W3185181104 @default.
• W3157294174 cites W642705691 @default.
• W3157294174 doi "https://doi.org/10.1038/s41598-021-88260-1" @default.
• W3157294174 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8079405" @default.
• W3157294174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33907227" @default.
• W3157294174 hasPublicationYear "2021" @default.
• W3157294174 type Work @default.
• W3157294174 sameAs 3157294174 @default.
• W3157294174 citedByCount "5" @default.
• W3157294174 countsByYear W31572941742022 @default.
• W3157294174 countsByYear W31572941742023 @default.
• W3157294174 crossrefType "journal-article" @default.
• W3157294174 hasAuthorship W3157294174A5000752192 @default.
• W3157294174 hasAuthorship W3157294174A5026961997 @default.
• W3157294174 hasAuthorship W3157294174A5045339907 @default.
• W3157294174 hasAuthorship W3157294174A5047516625 @default.
• W3157294174 hasAuthorship W3157294174A5050110012 @default.
• W3157294174 hasAuthorship W3157294174A5065681889 @default.
• W3157294174 hasAuthorship W3157294174A5069196659 @default.
• W3157294174 hasAuthorship W3157294174A5073810747 @default.
• W3157294174 hasAuthorship W3157294174A5081463984 @default.
• W3157294174 hasAuthorship W3157294174A5082731567 @default.
• W3157294174 hasBestOaLocation W31572941741 @default.
• W3157294174 hasConcept C109316439 @default.
• W3157294174 hasConcept C126322002 @default.
• W3157294174 hasConcept C154317977 @default.
• W3157294174 hasConcept C185592680 @default.
• W3157294174 hasConcept C202751555 @default.
• W3157294174 hasConcept C2776636253 @default.
• W3157294174 hasConcept C2776694085 @default.
• W3157294174 hasConcept C2777752497 @default.
• W3157294174 hasConcept C2779703632 @default.
• W3157294174 hasConcept C2780820201 @default.
• W3157294174 hasConcept C2781303535 @default.
• W3157294174 hasConcept C55493867 @default.
• W3157294174 hasConcept C71924100 @default.
• W3157294174 hasConcept C98274493 @default.
• W3157294174 hasConceptScore W3157294174C109316439 @default.
• W3157294174 hasConceptScore W3157294174C126322002 @default.
• W3157294174 hasConceptScore W3157294174C154317977 @default.
• W3157294174 hasConceptScore W3157294174C185592680 @default.
• W3157294174 hasConceptScore W3157294174C202751555 @default.
• W3157294174 hasConceptScore W3157294174C2776636253 @default.
• W3157294174 hasConceptScore W3157294174C2776694085 @default.
• W3157294174 hasConceptScore W3157294174C2777752497 @default.
• W3157294174 hasConceptScore W3157294174C2779703632 @default.
• W3157294174 hasConceptScore W3157294174C2780820201 @default.
• W3157294174 hasConceptScore W3157294174C2781303535 @default.
• W3157294174 hasConceptScore W3157294174C55493867 @default.
• W3157294174 hasConceptScore W3157294174C71924100 @default.
• W3157294174 hasConceptScore W3157294174C98274493 @default.
• W3157294174 hasIssue "1" @default.
• W3157294174 hasLocation W31572941741 @default.
• W3157294174 hasLocation W31572941742 @default.
• W3157294174 hasLocation W31572941743 @default.
• W3157294174 hasLocation W31572941744 @default.
• W3157294174 hasOpenAccess W3157294174 @default.
• W3157294174 hasPrimaryLocation W31572941741 @default.

• next