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• W3157305514 abstract "There has been increasing interest in wireless, miniaturized implantable medical devices for in vivo and in situ physiological monitoring. Here, we present such an implant that uses a conventional ultrasound imager for wireless powering and data communication and acts as a probe for real-time temperature sensing, including the monitoring of body temperature and temperature changes resulting from therapeutic application of ultrasound. The sub-0.1-mm3, sub-1-nW device, referred to as a mote, achieves aggressive miniaturization through the monolithic integration of a custom low-power temperature sensor chip with a microscale piezoelectric transducer fabricated on top of the chip. The small displaced volume of these motes allows them to be implanted or injected using minimally invasive techniques with improved biocompatibility. We demonstrate their sensing functionality in vivo for an ultrasound neurostimulation procedure in mice. Our motes have the potential to be adapted to the distributed and localized sensing of other clinically relevant physiological parameters." @default.
• W3157305514 created "2021-05-10" @default.
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• W3157305514 date "2021-05-07" @default.
• W3157305514 modified "2023-10-10" @default.
• W3157305514 title "Application of a sub–0.1-mm ³ implantable mote for in vivo real-time wireless temperature sensing" @default.
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• W3157305514 doi "https://doi.org/10.1126/sciadv.abf6312" @default.
• W3157305514 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8104878" @default.
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• W3157305514 hasPublicationYear "2021" @default.
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