Matches in SemOpenAlex for { <https://semopenalex.org/work/W3157306516> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W3157306516 abstract "Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine associated with genetic susceptibility and alterations in the intestinal microbiome. Multiomics data developed and analyzed over the last several decades have yielded an unprecedented amount of genetic and microbial data. But how do we pinpoint mechanistic insight into the host-microbe relationship that will ultimately enable better care for patients with IBD? In this issue of the JCI, Grasberger et al. undertook a major decoding effort to decipher this multiomic data matrix. The authors analyzed anonymized data from more than 2800 individuals to discover a link between heterozygous carriers of deleterious DUOX2 variants and high levels of plasma IL-17C. These findings provide an example of how harnessing big data can drive mechanistic discovery to define disease biomarkers that have the potential to improve clinical care in IBD." @default.
- W3157306516 created "2021-05-10" @default.
- W3157306516 creator A5008502344 @default.
- W3157306516 creator A5031846935 @default.
- W3157306516 date "2021-05-03" @default.
- W3157306516 modified "2023-10-17" @default.
- W3157306516 title "Decoding the matrix: multiomics reveals host-microbe biomarker for inflammatory bowel disease" @default.
- W3157306516 cites W2024629560 @default.
- W3157306516 cites W2367535883 @default.
- W3157306516 cites W2767830642 @default.
- W3157306516 cites W2914073093 @default.
- W3157306516 cites W2944421619 @default.
- W3157306516 cites W3135108552 @default.
- W3157306516 doi "https://doi.org/10.1172/jci148902" @default.
- W3157306516 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8087194" @default.
- W3157306516 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33938448" @default.
- W3157306516 hasPublicationYear "2021" @default.
- W3157306516 type Work @default.
- W3157306516 sameAs 3157306516 @default.
- W3157306516 citedByCount "1" @default.
- W3157306516 countsByYear W31573065162022 @default.
- W3157306516 crossrefType "journal-article" @default.
- W3157306516 hasAuthorship W3157306516A5008502344 @default.
- W3157306516 hasAuthorship W3157306516A5031846935 @default.
- W3157306516 hasBestOaLocation W31573065161 @default.
- W3157306516 hasConcept C142724271 @default.
- W3157306516 hasConcept C143121216 @default.
- W3157306516 hasConcept C164614171 @default.
- W3157306516 hasConcept C203014093 @default.
- W3157306516 hasConcept C2778260677 @default.
- W3157306516 hasConcept C2779134260 @default.
- W3157306516 hasConcept C2780479503 @default.
- W3157306516 hasConcept C2781197716 @default.
- W3157306516 hasConcept C3019978661 @default.
- W3157306516 hasConcept C54355233 @default.
- W3157306516 hasConcept C60644358 @default.
- W3157306516 hasConcept C70721500 @default.
- W3157306516 hasConcept C71924100 @default.
- W3157306516 hasConcept C86803240 @default.
- W3157306516 hasConceptScore W3157306516C142724271 @default.
- W3157306516 hasConceptScore W3157306516C143121216 @default.
- W3157306516 hasConceptScore W3157306516C164614171 @default.
- W3157306516 hasConceptScore W3157306516C203014093 @default.
- W3157306516 hasConceptScore W3157306516C2778260677 @default.
- W3157306516 hasConceptScore W3157306516C2779134260 @default.
- W3157306516 hasConceptScore W3157306516C2780479503 @default.
- W3157306516 hasConceptScore W3157306516C2781197716 @default.
- W3157306516 hasConceptScore W3157306516C3019978661 @default.
- W3157306516 hasConceptScore W3157306516C54355233 @default.
- W3157306516 hasConceptScore W3157306516C60644358 @default.
- W3157306516 hasConceptScore W3157306516C70721500 @default.
- W3157306516 hasConceptScore W3157306516C71924100 @default.
- W3157306516 hasConceptScore W3157306516C86803240 @default.
- W3157306516 hasIssue "9" @default.
- W3157306516 hasLocation W31573065161 @default.
- W3157306516 hasLocation W31573065162 @default.
- W3157306516 hasLocation W31573065163 @default.
- W3157306516 hasOpenAccess W3157306516 @default.
- W3157306516 hasPrimaryLocation W31573065161 @default.
- W3157306516 hasRelatedWork W2070285775 @default.
- W3157306516 hasRelatedWork W2073878479 @default.
- W3157306516 hasRelatedWork W2124908533 @default.
- W3157306516 hasRelatedWork W2258300052 @default.
- W3157306516 hasRelatedWork W2408939568 @default.
- W3157306516 hasRelatedWork W2409879998 @default.
- W3157306516 hasRelatedWork W2412773332 @default.
- W3157306516 hasRelatedWork W2418837291 @default.
- W3157306516 hasRelatedWork W2512626908 @default.
- W3157306516 hasRelatedWork W4294408689 @default.
- W3157306516 hasVolume "131" @default.
- W3157306516 isParatext "false" @default.
- W3157306516 isRetracted "false" @default.
- W3157306516 magId "3157306516" @default.
- W3157306516 workType "article" @default.