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- W3157325689 abstract "Abstract Rice beverages are traditionally prepared and consumed popularly by the different ethnic groups of North East India. To investigate its effects on behavior, mice were treated with different fractions of rice beverage that included the beverage as a whole, insoluble and soluble fractions. Intragastric treatments of these fractions were given to the mice (n=6 per group) for 30 days and behavioral studies were performed on elevated plus and Y maze to evaluate anxiety and spatial memory, respectively. Next generation sequencing of metagenomic DNA of the beverage indicated presence of 157 OTUs and 26 bacterial genera were dominant with an abundance of 0.1%. The insoluble fraction treated animals showed lowest anxiety like symptoms. Spatial memory improved in all the treatments compared to the control, of which the rice beverage treatment showed the highest levels ( p <0.05). Gas chromatography and mass spectroscopy-based metabolite profiling of the beverage revealed 10 alcohols, 29 sachharides, 43 acids and 13 amino acids. Findings of this study suggest a positive effect of rice beverage components on anxiety and spatial memory of mice." @default.
- W3157325689 created "2021-05-10" @default.
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- W3157325689 date "2021-05-02" @default.
- W3157325689 modified "2023-09-23" @default.
- W3157325689 title "Fractions of traditionally brewed rice beverage ameliorate anxiety and improve spatial memory in mice" @default.
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- W3157325689 doi "https://doi.org/10.1101/2021.05.01.442231" @default.
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