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- W3157337586 endingPage "1118" @default.
- W3157337586 startingPage "1118" @default.
- W3157337586 abstract "Viral pathogens often exploit host cell regulatory and signaling pathways to ensure an optimal environment for growth and survival. Several studies have suggested that 5′-adenosine monophosphate-activated protein kinase (AMPK), an intracellular serine/threonine kinase, plays a significant role in the modulation of infection. Traditionally, AMPK is a key energy regulator of cell growth and proliferation, host autophagy, stress responses, metabolic reprogramming, mitochondrial homeostasis, fatty acid β-oxidation and host immune function. In this review, we highlight the modulation of host AMPK by various viruses under physiological conditions. These intracellular pathogens trigger metabolic changes altering AMPK signaling activity that then facilitates or inhibits viral replication. Considering the COVID-19 pandemic, understanding the regulation of AMPK signaling following infection can shed light on the development of more effective therapeutic strategies against viral infectious diseases." @default.
- W3157337586 created "2021-05-10" @default.
- W3157337586 creator A5026035028 @default.
- W3157337586 creator A5029853760 @default.
- W3157337586 creator A5074780664 @default.
- W3157337586 date "2021-05-06" @default.
- W3157337586 modified "2023-10-18" @default.
- W3157337586 title "Multifaceted Role of AMPK in Viral Infections" @default.
- W3157337586 cites W1479552731 @default.
- W3157337586 cites W1546765124 @default.
- W3157337586 cites W1559210758 @default.
- W3157337586 cites W1644352612 @default.
- W3157337586 cites W1801817957 @default.
- W3157337586 cites W1879933282 @default.
- W3157337586 cites W1919113021 @default.
- W3157337586 cites W1934732859 @default.
- W3157337586 cites W1966339676 @default.
- W3157337586 cites W1970637701 @default.
- W3157337586 cites W1974918249 @default.
- W3157337586 cites W1983834588 @default.
- W3157337586 cites W1985362216 @default.
- W3157337586 cites W1987849310 @default.
- W3157337586 cites W1989863106 @default.
- W3157337586 cites W1990704025 @default.
- W3157337586 cites W1992832263 @default.
- W3157337586 cites W1993431258 @default.
- W3157337586 cites W1993962581 @default.
- W3157337586 cites W1995381409 @default.
- W3157337586 cites W1996735611 @default.
- W3157337586 cites W2001568034 @default.
- W3157337586 cites W2004814508 @default.
- W3157337586 cites W2006216342 @default.
- W3157337586 cites W2010564619 @default.
- W3157337586 cites W2014255712 @default.
- W3157337586 cites W2014885180 @default.
- W3157337586 cites W2019054179 @default.
- W3157337586 cites W2020100023 @default.
- W3157337586 cites W2023686098 @default.
- W3157337586 cites W2028591676 @default.
- W3157337586 cites W2030817984 @default.
- W3157337586 cites W2031315554 @default.
- W3157337586 cites W2033355416 @default.
- W3157337586 cites W2038227076 @default.
- W3157337586 cites W2047581693 @default.
- W3157337586 cites W2053543225 @default.
- W3157337586 cites W2060102571 @default.
- W3157337586 cites W2060125494 @default.
- W3157337586 cites W2061680286 @default.
- W3157337586 cites W2067872036 @default.
- W3157337586 cites W2069408589 @default.
- W3157337586 cites W2072131094 @default.
- W3157337586 cites W2076801755 @default.
- W3157337586 cites W2077929218 @default.
- W3157337586 cites W2080481362 @default.
- W3157337586 cites W2081712103 @default.
- W3157337586 cites W2081920342 @default.
- W3157337586 cites W2085566385 @default.
- W3157337586 cites W2091469763 @default.
- W3157337586 cites W2095640779 @default.
- W3157337586 cites W2103851013 @default.
- W3157337586 cites W2111152746 @default.
- W3157337586 cites W2112243729 @default.
- W3157337586 cites W2112668580 @default.
- W3157337586 cites W2123694551 @default.
- W3157337586 cites W2126104284 @default.
- W3157337586 cites W2132463840 @default.
- W3157337586 cites W2160309916 @default.
- W3157337586 cites W2160615487 @default.
- W3157337586 cites W2166025848 @default.
- W3157337586 cites W2166251170 @default.
- W3157337586 cites W2170054980 @default.
- W3157337586 cites W2170880090 @default.
- W3157337586 cites W2170880806 @default.
- W3157337586 cites W2174118934 @default.
- W3157337586 cites W2202812349 @default.
- W3157337586 cites W2259398295 @default.
- W3157337586 cites W2266158144 @default.
- W3157337586 cites W2269336718 @default.
- W3157337586 cites W2290239426 @default.
- W3157337586 cites W2294268013 @default.
- W3157337586 cites W2297772307 @default.
- W3157337586 cites W2330858298 @default.
- W3157337586 cites W2346430479 @default.
- W3157337586 cites W2346523635 @default.
- W3157337586 cites W2406564816 @default.
- W3157337586 cites W2412181342 @default.
- W3157337586 cites W2422314397 @default.
- W3157337586 cites W2472054870 @default.
- W3157337586 cites W2475015499 @default.
- W3157337586 cites W2487691261 @default.
- W3157337586 cites W2508012617 @default.
- W3157337586 cites W2549713124 @default.
- W3157337586 cites W2553012396 @default.
- W3157337586 cites W2553190944 @default.
- W3157337586 cites W2560394908 @default.
- W3157337586 cites W2565733388 @default.
- W3157337586 cites W2582151849 @default.
- W3157337586 cites W2589445559 @default.