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- W3157398013 abstract "Insulin therapy is one of the most widely used methods for antidiabetic treatment. In contrast with manually controlled open-loop insulin delivery devices, closed-loop devices are continuously and automatically operated to mimic the natural insulin production process of the pancreas. Insulin pen and pumps are conventional open-loop devices that deliver insulin via subcutaneous injections. Insulin inhaler and tablets are novel devices that enable non-invasive insulin administration. The discomfort and risk of hypoglycemia associated with open-loop administrations facilitated the investigation of glucose-responsive closed-loop devices. Smart insulin pumps with a continuous glucose monitoring (CGM) is able to sense the real-time glucose levels and pause insulin infusion when necessary. Nonelectronic nanotechnology-enabled devices, such as microneedle array patches and hydrogel-containing catheters, demonstrate great value in the future of potential diabetes treatment." @default.
- W3157398013 created "2021-05-10" @default.
- W3157398013 creator A5017994666 @default.
- W3157398013 date "2021-01-01" @default.
- W3157398013 modified "2023-09-25" @default.
- W3157398013 title "Insulin delivery devices for diabetes mellitus from open-loop to closed-loop" @default.
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- W3157398013 doi "https://doi.org/10.1063/5.0049209" @default.
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