FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3157448051> ?p ?o ?g. }

• W3157448051 endingPage "338" @default.
• W3157448051 startingPage "322" @default.
• W3157448051 abstract "Several reports have associated the severe Coronavirus disease-2019 (sCOVID-19) with secondary-hemophagocytic lymphohistiocytosis (sHLH) and proposed utilizing the hemophagocytic syndrome diagnostic score (HScore) for sCOVID-19 patients. We conducted a systematic review and meta-analysis to find the possible association of HScore parameters with severity in COVID-19 patients.A systematic search was performed in Medline via PubMed, EMBASE, and Cochrane databases using all HScore and COVID-19 keywords. The studies were all from 2020, and the study language was limited to English. The records were screened based on inclusion/exclusion criteria. Random/fixed-effect models were employed for meta-analysis, based on the I2 index of parameters. The pooled mean differences were estimated for continuous parameters. The pooled odds-ratio was estimated for fever. The level of significance was set at 0.05.Eighteen studies (comprising 2459 patients) out of 26151 screened studies were included in this meta-analysis. The results showed that the level of leukocyte, neutrophil, aspartate transaminase (AST), ferritin, and fibrinogen were significantly higher in sCOVID-19 patients than in non-severe ones. Significant lower levels of lymphocyte, platelet, and hemoglobin were also found in sCOVID-19 patients than non-severe patients. Fever was nearly associated with two times increased odds of sCOVID-19 (P=0.051).Lymphopenia, thrombocytopenia, hypohemoglobinemia, hyperferritinemia, high levels of AST, and fever are common features of both sCOVID-19 and HLH. However, the leukocytosis, neutrophilia, and hyperfibrinogenemia found in sCOVID-19 are in contrast with HScore. Conclusively, HScore parameters could be risk factors for sCOVID-19. However, some parameters' roles are contradictory, suggesting the need for further investigation and a new way of HScore interpretation in sCOVID-19 patients.A preprint of this study was published at https://www.researchsquare.com/article/rs-54490/v2." @default.
• W3157448051 created "2021-05-10" @default.
• W3157448051 creator A5010862393 @default.
• W3157448051 creator A5042552132 @default.
• W3157448051 creator A5051205425 @default.
• W3157448051 creator A5055005898 @default.
• W3157448051 creator A5065171370 @default.
• W3157448051 creator A5072547331 @default.
• W3157448051 creator A5085453372 @default.
• W3157448051 date "2021-09-01" @default.
• W3157448051 modified "2023-09-27" @default.
• W3157448051 title "Association of HScore Parameters with Severe COVID-19: A Systematic Review and Meta-Analysis." @default.
• W3157448051 cites W1505641753 @default.
• W3157448051 cites W1534181333 @default.
• W3157448051 cites W1974590102 @default.
• W3157448051 cites W2019367280 @default.
• W3157448051 cites W2041184642 @default.
• W3157448051 cites W2045686436 @default.
• W3157448051 cites W2072443528 @default.
• W3157448051 cites W2122161660 @default.
• W3157448051 cites W2161374186 @default.
• W3157448051 cites W2170892587 @default.
• W3157448051 cites W2444620062 @default.
• W3157448051 cites W2560393808 @default.
• W3157448051 cites W2574674925 @default.
• W3157448051 cites W2763145104 @default.
• W3157448051 cites W3007460166 @default.
• W3157448051 cites W3008090866 @default.
• W3157448051 cites W3009951436 @default.
• W3157448051 cites W3010338568 @default.
• W3157448051 cites W3011610993 @default.
• W3157448051 cites W3012290165 @default.
• W3157448051 cites W3012421327 @default.
• W3157448051 cites W3013376849 @default.
• W3157448051 cites W3013385173 @default.
• W3157448051 cites W3014003872 @default.
• W3157448051 cites W3014695022 @default.
• W3157448051 cites W3015407900 @default.
• W3157448051 cites W3015696390 @default.
• W3157448051 cites W3016010853 @default.
• W3157448051 cites W3016127406 @default.
• W3157448051 cites W3017110669 @default.
• W3157448051 cites W3017432371 @default.
• W3157448051 cites W3017734961 @default.
• W3157448051 cites W3017879449 @default.
• W3157448051 cites W3018868982 @default.
• W3157448051 cites W3019039411 @default.
• W3157448051 cites W3019830619 @default.
• W3157448051 cites W3020247120 @default.
• W3157448051 cites W3020995110 @default.
• W3157448051 cites W3021302768 @default.
• W3157448051 cites W3023784167 @default.
• W3157448051 cites W3023836455 @default.
• W3157448051 cites W3023855559 @default.
• W3157448051 cites W3024222526 @default.
• W3157448051 cites W3024507395 @default.
• W3157448051 cites W3024875760 @default.
• W3157448051 cites W3024894644 @default.
• W3157448051 cites W3026888299 @default.
• W3157448051 cites W3027668992 @default.
• W3157448051 cites W3029640851 @default.
• W3157448051 cites W3030630152 @default.
• W3157448051 cites W3033842431 @default.
• W3157448051 cites W3035062828 @default.
• W3157448051 cites W3035651200 @default.
• W3157448051 cites W3035725567 @default.
• W3157448051 cites W3036121018 @default.
• W3157448051 cites W3036290311 @default.
• W3157448051 cites W3038063455 @default.
• W3157448051 cites W3040395637 @default.
• W3157448051 cites W3041882591 @default.
• W3157448051 cites W3043397448 @default.
• W3157448051 cites W3044231876 @default.
• W3157448051 cites W3045171832 @default.
• W3157448051 cites W3047028170 @default.
• W3157448051 cites W3070973952 @default.
• W3157448051 cites W3085260439 @default.
• W3157448051 cites W3087773878 @default.
• W3157448051 cites W3095639553 @default.
• W3157448051 doi "https://doi.org/10.30476/ijms.2021.88404.1910" @default.
• W3157448051 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8438337" @default.
• W3157448051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34539007" @default.
• W3157448051 hasPublicationYear "2021" @default.
• W3157448051 type Work @default.
• W3157448051 sameAs 3157448051 @default.
• W3157448051 citedByCount "2" @default.
• W3157448051 countsByYear W31574480512022 @default.
• W3157448051 crossrefType "journal-article" @default.
• W3157448051 hasAuthorship W3157448051A5010862393 @default.
• W3157448051 hasAuthorship W3157448051A5042552132 @default.
• W3157448051 hasAuthorship W3157448051A5051205425 @default.
• W3157448051 hasAuthorship W3157448051A5055005898 @default.
• W3157448051 hasAuthorship W3157448051A5065171370 @default.
• W3157448051 hasAuthorship W3157448051A5072547331 @default.
• W3157448051 hasAuthorship W3157448051A5085453372 @default.
• W3157448051 hasConcept C126322002 @default.
• W3157448051 hasConcept C156957248 @default.
• W3157448051 hasConcept C160160445 @default.

• next