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- W3157509276 startingPage "129" @default.
- W3157509276 abstract "The crucial point of chronic hepatopathies is represented by their capacity for fibrotic evolution. Recent studies have highlighted the role of serotonin (5-HT) in the development of liver fibrogenesis. Serotonin is a biogenic amine that exerts its activity through a family of seven receptors and it regulates many key factors involved in the tissue repair process, proliferation and apoptosis of activated hepatic stellate cells (HSCs). Moreover, activated HSCs express a serotonin transporter protein (SERT). The intestinal microbiota plays an important role in the homeostasis of 5-HT, affecting the SERT and/or the expression of the 5-HT receptors. Changes in the intestinal microbiota through the intestine–liver axis can regulate local 5-HT concentrations in the portal blood. This chapter focuses on the relationship between serotonin and its pathways in hepatic fibrogenesis during chronic hepatopathies, and development of hepatocellular carcinoma, with specific attention on serotonin metabolism and its influence in gut–liver axis outflow." @default.
- W3157509276 created "2021-05-10" @default.
- W3157509276 creator A5027938455 @default.
- W3157509276 creator A5050902164 @default.
- W3157509276 creator A5079699993 @default.
- W3157509276 date "2021-01-01" @default.
- W3157509276 modified "2023-09-23" @default.
- W3157509276 title "Gut-liver The role of serotonin and its pathways in hepatic fibrogenesis" @default.
- W3157509276 cites W130054925 @default.
- W3157509276 cites W1420654867 @default.
- W3157509276 cites W1505584712 @default.
- W3157509276 cites W1520624885 @default.
- W3157509276 cites W1528348540 @default.
- W3157509276 cites W1539707693 @default.
- W3157509276 cites W1540477295 @default.
- W3157509276 cites W1549115605 @default.
- W3157509276 cites W1642639203 @default.
- W3157509276 cites W1907864108 @default.
- W3157509276 cites W1932150911 @default.
- W3157509276 cites W1932668123 @default.
- W3157509276 cites W1965662512 @default.
- W3157509276 cites W1967330368 @default.
- W3157509276 cites W1970621949 @default.
- W3157509276 cites W1974834526 @default.
- W3157509276 cites W1977282936 @default.
- W3157509276 cites W1980855968 @default.
- W3157509276 cites W1981815626 @default.
- W3157509276 cites W1983045415 @default.
- W3157509276 cites W1983086656 @default.
- W3157509276 cites W1986577643 @default.
- W3157509276 cites W1986606398 @default.
- W3157509276 cites W1988304525 @default.
- W3157509276 cites W1988760657 @default.
- W3157509276 cites W1990147202 @default.
- W3157509276 cites W1993518161 @default.
- W3157509276 cites W1995838863 @default.
- W3157509276 cites W1996234987 @default.
- W3157509276 cites W1997225712 @default.
- W3157509276 cites W2000435786 @default.
- W3157509276 cites W2000904449 @default.
- W3157509276 cites W2001216618 @default.
- W3157509276 cites W2003099302 @default.
- W3157509276 cites W2003135973 @default.
- W3157509276 cites W2005534453 @default.
- W3157509276 cites W2007486557 @default.
- W3157509276 cites W2010180179 @default.
- W3157509276 cites W2010274889 @default.
- W3157509276 cites W2010910182 @default.
- W3157509276 cites W2011663436 @default.
- W3157509276 cites W2014980326 @default.
- W3157509276 cites W2017024005 @default.
- W3157509276 cites W2019281511 @default.
- W3157509276 cites W2023250239 @default.
- W3157509276 cites W2027315920 @default.
- W3157509276 cites W2029174913 @default.
- W3157509276 cites W2029943794 @default.
- W3157509276 cites W2030102531 @default.
- W3157509276 cites W2032230795 @default.
- W3157509276 cites W2033386838 @default.
- W3157509276 cites W2038479423 @default.
- W3157509276 cites W2039836319 @default.
- W3157509276 cites W2043598404 @default.
- W3157509276 cites W204513865 @default.
- W3157509276 cites W2046037975 @default.
- W3157509276 cites W2053744043 @default.
- W3157509276 cites W2060148370 @default.
- W3157509276 cites W2061812948 @default.
- W3157509276 cites W2063053815 @default.
- W3157509276 cites W2064855192 @default.
- W3157509276 cites W2064866402 @default.
- W3157509276 cites W2064912565 @default.
- W3157509276 cites W2065840120 @default.
- W3157509276 cites W2066901708 @default.
- W3157509276 cites W2067357799 @default.
- W3157509276 cites W2070495192 @default.
- W3157509276 cites W2071694198 @default.
- W3157509276 cites W2073044724 @default.
- W3157509276 cites W2073413372 @default.
- W3157509276 cites W2073534408 @default.
- W3157509276 cites W2080308963 @default.
- W3157509276 cites W2080325240 @default.
- W3157509276 cites W2080347540 @default.
- W3157509276 cites W2081622555 @default.
- W3157509276 cites W2081966783 @default.
- W3157509276 cites W2084722601 @default.
- W3157509276 cites W2084879269 @default.
- W3157509276 cites W2089285664 @default.
- W3157509276 cites W2092655681 @default.
- W3157509276 cites W2093270469 @default.
- W3157509276 cites W2097063773 @default.
- W3157509276 cites W2097566770 @default.
- W3157509276 cites W2103090913 @default.
- W3157509276 cites W2103568206 @default.
- W3157509276 cites W2104048513 @default.
- W3157509276 cites W2107237727 @default.
- W3157509276 cites W2109416272 @default.
- W3157509276 cites W2110705719 @default.
- W3157509276 cites W2111858134 @default.