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- W3157544718 abstract "Anecdotal cases of the so-called “wrap-around” appearance in non-Hodgkin lymphoma (NHL) of the spine exist in the medical literature. In this paper, we looked at the prevalence of this imaging feature in our institutional cases. We screened our institutional database for biopsy-proven NHL. Our inclusion criteria were the histologically confirmed diagnosis of NHL involving any vertebra, available magnetic resonance imaging of the affected site, and a positive wrap-around sign. Exclusion criteria included lymphoma cases without the wrap-around sign and/or histology other than NHL. We subdivided the cases into 3 groups: 1) lymphoma wrapped around the vertebral body; 2) the posterior elements alone; or 3) both the vertebral body and posterior elements. Our search identified 147 cases of NHL in which a confirmatory biopsy at the primary tumor site was available. Of those, 23 cases fulfilled the inclusion criteria (16 men and 7 women with average age at diagnosis of 63.3 years), yielding prevalence of 15.6% in our series. Most commonly the lymphoma involved the vertebral body with or without some involvement of the posterior vertebral elements ( n = 20, 86.9%), followed by posterior vertebral elements ( n = 2, 8.7%). One remaining case (4.4%) had lymphoma involving the anterior vertebral body and posterior elements. Findings of our pilot study indicated that the wrap-around sign in cases of NHL could be helpful diagnostically. This sign may be frequently under-recognized, leading to potential for a diagnostic dilemma on imaging. Larger studies are necessary to obtain more precise information about the prevalence of the wrap-around sign." @default.
- W3157544718 created "2021-05-10" @default.
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- W3157544718 date "2021-07-01" @default.
- W3157544718 modified "2023-09-24" @default.
- W3157544718 title "“Wrap-Around Sign” in Non-Hodgkin Lymphoma of the Spine: A Common yet Overlooked Imaging Feature?" @default.
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- W3157544718 doi "https://doi.org/10.1016/j.wneu.2021.04.060" @default.
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