FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W315764148> ?p ?o ?g. }

• W315764148 endingPage "844" @default.
• W315764148 startingPage "837" @default.
• W315764148 abstract "To determine the influence of inflammation and topical treatment with 5-aminosalicylic acid or prednisolone on arachidonic acid metabolism in vivo, we carried out a double-blind controlled study on the release of prostaglandin E2 and leukotriene B4 to the rectal lumen in 24 consecutive patients with proven distally located ulcerative colitis. Before and at days 15 and 29 a dialysis bag was placed in the emptied rectum for 4 h prior to assessing clinical, endoscopic, and histologic disease activity. A single enema was given daily at bedtime (1 g 5-aminosalicylic acid or 25 mg prednisolone) until complete remission or for a maximum of 4 wk. Clinical and endoscopic remission was obtained in 16 (7 on 5-aminosalicylic acid) and 11 (3 on 5-aminosalicylic acid) patients, respectively. Luminal concentrations of prostaglandin E2 and leukotriene B4 were positively correlated to disease activity and significantly decreased among the prednisolone-treated patients. In both treatment groups a decrease toward normal levels occurred in patients responding to therapy. In retrospect, the pretreatment prostaglandin E2 and leukotriene B4 levels were significantly higher in patients not responding to therapy than in those improving during treatment. In conclusion, luminal prostaglandin E2 and leukotriene B4 levels may prove more useful predictors of the outcome of treatment in relapsing ulcerative colitis than clinical indices of disease activity." @default.
• W315764148 created "2016-06-24" @default.
• W315764148 creator A5001037620 @default.
• W315764148 creator A5007893618 @default.
• W315764148 creator A5017167053 @default.
• W315764148 creator A5032961023 @default.
• W315764148 date "1986-10-01" @default.
• W315764148 modified "2023-10-18" @default.
• W315764148 title "Effects of topical 5-aminosalicylic acid and prednisolone on prostaglandin E2 and leukotriene B4 levels determined by equilibrium in vivo dialysis of rectum in relapsing ulcerative colitis" @default.
• W315764148 cites W1465188541 @default.
• W315764148 cites W1662486898 @default.
• W315764148 cites W1900976786 @default.
• W315764148 cites W1979215922 @default.
• W315764148 cites W1979915837 @default.
• W315764148 cites W1985485512 @default.
• W315764148 cites W1988045811 @default.
• W315764148 cites W1989701577 @default.
• W315764148 cites W1999197985 @default.
• W315764148 cites W2022445623 @default.
• W315764148 cites W2024513902 @default.
• W315764148 cites W2047332731 @default.
• W315764148 cites W2056540045 @default.
• W315764148 cites W2056817635 @default.
• W315764148 cites W2069768487 @default.
• W315764148 cites W2074618658 @default.
• W315764148 cites W2078077899 @default.
• W315764148 cites W2081067304 @default.
• W315764148 cites W2088140807 @default.
• W315764148 cites W2091569846 @default.
• W315764148 cites W2094791820 @default.
• W315764148 cites W2095754840 @default.
• W315764148 cites W2107638998 @default.
• W315764148 cites W2127810970 @default.
• W315764148 cites W2130387436 @default.
• W315764148 cites W2135231814 @default.
• W315764148 cites W2138965033 @default.
• W315764148 cites W2166453553 @default.
• W315764148 cites W2166525518 @default.
• W315764148 cites W2177594905 @default.
• W315764148 cites W2580931000 @default.
• W315764148 cites W4300582720 @default.
• W315764148 doi "https://doi.org/10.1016/0016-5085(86)90684-0" @default.
• W315764148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3017804" @default.
• W315764148 hasPublicationYear "1986" @default.
• W315764148 type Work @default.
• W315764148 sameAs 315764148 @default.
• W315764148 citedByCount "245" @default.
• W315764148 countsByYear W3157641482012 @default.
• W315764148 countsByYear W3157641482013 @default.
• W315764148 countsByYear W3157641482014 @default.
• W315764148 countsByYear W3157641482015 @default.
• W315764148 countsByYear W3157641482016 @default.
• W315764148 countsByYear W3157641482017 @default.
• W315764148 countsByYear W3157641482018 @default.
• W315764148 countsByYear W3157641482019 @default.
• W315764148 countsByYear W3157641482021 @default.
• W315764148 countsByYear W3157641482022 @default.
• W315764148 crossrefType "journal-article" @default.
• W315764148 hasAuthorship W315764148A5001037620 @default.
• W315764148 hasAuthorship W315764148A5007893618 @default.
• W315764148 hasAuthorship W315764148A5017167053 @default.
• W315764148 hasAuthorship W315764148A5032961023 @default.
• W315764148 hasConcept C126322002 @default.
• W315764148 hasConcept C134018914 @default.
• W315764148 hasConcept C181199279 @default.
• W315764148 hasConcept C185592680 @default.
• W315764148 hasConcept C2776206795 @default.
• W315764148 hasConcept C2776685179 @default.
• W315764148 hasConcept C2776715498 @default.
• W315764148 hasConcept C2776914184 @default.
• W315764148 hasConcept C2777956040 @default.
• W315764148 hasConcept C2778078955 @default.
• W315764148 hasConcept C2778260677 @default.
• W315764148 hasConcept C2779134260 @default.
• W315764148 hasConcept C2780479503 @default.
• W315764148 hasConcept C2781074409 @default.
• W315764148 hasConcept C55493867 @default.
• W315764148 hasConcept C71924100 @default.
• W315764148 hasConcept C90924648 @default.
• W315764148 hasConceptScore W315764148C126322002 @default.
• W315764148 hasConceptScore W315764148C134018914 @default.
• W315764148 hasConceptScore W315764148C181199279 @default.
• W315764148 hasConceptScore W315764148C185592680 @default.
• W315764148 hasConceptScore W315764148C2776206795 @default.
• W315764148 hasConceptScore W315764148C2776685179 @default.
• W315764148 hasConceptScore W315764148C2776715498 @default.
• W315764148 hasConceptScore W315764148C2776914184 @default.
• W315764148 hasConceptScore W315764148C2777956040 @default.
• W315764148 hasConceptScore W315764148C2778078955 @default.
• W315764148 hasConceptScore W315764148C2778260677 @default.
• W315764148 hasConceptScore W315764148C2779134260 @default.
• W315764148 hasConceptScore W315764148C2780479503 @default.
• W315764148 hasConceptScore W315764148C2781074409 @default.
• W315764148 hasConceptScore W315764148C55493867 @default.
• W315764148 hasConceptScore W315764148C71924100 @default.
• W315764148 hasConceptScore W315764148C90924648 @default.
• W315764148 hasIssue "4" @default.
• W315764148 hasLocation W3157641481 @default.

• next