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- W3157661441 endingPage "185" @default.
- W3157661441 startingPage "174" @default.
- W3157661441 abstract "The introduction of clotting factor concentrates has substantially improved the lives of people with clotting factor deficiencies. Unfortunately, the transmission of blood-borne viral infections through these plasma-derived products led to a huge epidemic of human immunodeficiency virus and viral hepatitis in people with haemophilia (PWH). In a significant proportion of PWH exposed to these viruses, the ensuing decades-long chronic infection resulted in excess morbidity and mortality. Fortunately, developments in the safety of blood products, as well as vaccination and highly effective antiviral treatments have improved the prospects of PWH. The present article reviews the background of the viral hepatitis epidemic in PWH, the natural history of hepatitis B and C infections and their long-term management." @default.
- W3157661441 created "2021-05-10" @default.
- W3157661441 creator A5036115318 @default.
- W3157661441 creator A5041859079 @default.
- W3157661441 creator A5045668995 @default.
- W3157661441 creator A5048888596 @default.
- W3157661441 creator A5089276217 @default.
- W3157661441 date "2021-05-06" @default.
- W3157661441 modified "2023-10-17" @default.
- W3157661441 title "Viral hepatitis in haemophilia: historical perspective and current management" @default.
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